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Fmoc-N-amido-PEG6-acetic acid is a PEG linker containing a protected amino group and a carboxylic acid. The carboxylic acid can be reacted with amino groups in the presence of activators.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01954 | -- | $-- | Inquiry |
Fmoc-N-amido-PEG6-acetic acid, a versatile reagent commonly seen in peptide synthesis and bioconjugation applications, plays a pivotal role in advancing various fields. Here are four key applications:
Peptide Synthesis: Acting as a crucial linker in solid-phase peptide synthesis, Fmoc-N-amido-PEG6-acetic acid introduces a flexible spacer between peptides and the resin, streamlining the cleavage and purification processes. This intricate design leads to elevated yields and purities of synthesized peptides, especially beneficial for intricate or lengthy peptide chains.
Drug Delivery: In the realm of drug delivery enhancement, this compound proves its mettle by facilitating the modification of peptides and proteins for optimal drug delivery outcomes. By harnessing Fmoc-N-amido-PEG6-acetic acid, researchers can enhance the solubility, stability, and bioavailability of therapeutic molecules, ultimately enabling precise targeting and controlled release of drugs in vivo.
Bioconjugation: Delving into bioconjugation techniques, Fmoc-N-amido-PEG6-acetic acid emerges as a key player in linking biomolecules, such as proteins, antibodies, and nucleic acids, to solid supports or other functional groups. Its PEG moiety brings about flexibility and minimizes steric hindrance, ensuring efficient coupling reactions.
Surface Functionalization: At the frontier of surface functionalization, Fmoc-N-amido-PEG6-acetic acid finds utility in modifying surfaces like nanoparticles or biosensors. Through surface modification with this reagent, researchers can generate biocompatible surfaces that thwart undesired protein adsorption and boost specific interactions. This critical application shapes the development of advanced biomedical devices and sensor technologies.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
