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| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01140 | -- | $-- | Inquiry |
DSP Crosslinker, a chemical reagent facilitating covalent linkages between molecules, is an indispensable tool in a multitude of scientific pursuits. Here are four key applications of DSP Crosslinker:
Protein-Protein Interaction Studies: Widely utilized in the exploration of protein-protein interactions, DSP Crosslinker serves to forge stable complexes between interacting proteins. By covalently linking these proteins, researchers can capture fleeting interactions, subsequently subjecting the complex to analysis through methodologies like mass spectrometry or gel electrophoresis. This approach aids in the identification of interaction partners and enhances comprehension of the intricate functional networks operating within cells.
Immunoprecipitation Assays: Within immunoprecipitation assays, DSP Crosslinker plays a crucial role in fortifying antibody-antigen complexes. By crosslinking the antibody to the antigen, the resulting complex gains heightened resistance to dissociation during washing stages, elevating specificity and yield in the assay. This augmentation strengthens the reliability of immunoprecipitation as a potent investigative tool for scrutinizing protein function and localization.
Bioconjugation: Encompassing bioconjugation endeavors, DSP Crosslinker facilitates the attachment of biomolecules to diverse substrates, such as beads or surfaces. This process enables the fabrication of functionalized surfaces for applications spanning biosensors, diagnostic tools, and affinity purification systems. The capability to covalently link biomolecules ensures stability and specificity in these contexts, fostering advancements in biotechnological applications.
Structural Biology: Integral to the landscape of structural biology, DSP Crosslinker contributes to the crosslinking of proteins in their native conformations, facilitating structural studies utilizing techniques like X-ray crystallography or cryo-EM. By stabilizing the native protein complexes, researchers can glean more precise structural insights, a critical facet in unraveling protein functionality and devising therapeutic interventions.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
