SIA Crosslinker - CAS 39028-27-8

SIA Crosslinker - CAS 39028-27-8 Catalog number: BADC-01120

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SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

General Information

Category
ADCs Linker
Product Name
SIA Crosslinker
CAS
39028-27-8
Catalog Number
BADC-01120
Molecular Formula
C6H6INO4
Molecular Weight
283.02 g/mol

Chemical Structure

  • SIA Crosslinker
Purity
>99.3%
Appearance
White to light yellow powder to crystal
Synonyms
2,5-Dioxopyrrolidin-1-yl 2-iodoacetate; N-Succinimidyl Iodoacetate; Iodoacetic acid N-hydroxysuccinimide ester
Solubility
10 mM in DMSO
Storage
-20°C
Shelf Life
0-4℃ for short term (days to weeks), or -20℃ for long term (months).
Shipping
Room temperature
Boiling Point
315.6±44.0 °C (Predicted)
Melting Point
148 °C
Density
2.110±0.10 g/cm3 (Predicted)
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CI
InChI Key
VRDGQQTWSGDXCU-UHFFFAOYSA-N
InChI
InChI=1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2

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Historical Records: Lycorine HCl | 4-succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene | 5-Maleimidovalericacid-NHS | Aminooxy-PEG3-azide | 4-Formyl-N-(2-(naphthalen-2-Yloxy)ethyl)benzamide | Triptolide | Ald-Ph-amido-PEG3-C2-Pfp ester | Lappaconitine Hydrobromide | Bis-PEG13-NHS ester | 4-Formyl-N-(2-Phenoxyethyl)benzamide | SIA Crosslinker
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