Fmoc-Gly-Gly-Gly-Gly-OH - CAS 1001202-16-9

Fmoc-Gly-Gly-Gly-Gly-OH - CAS 1001202-16-9 Catalog number: BADC-01586

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Fmoc-Gly-Gly-Gly-Gly-OH is an inherent constituent within the biomedical realm. It serves as a pivotal foundational constituent in the conduction of peptide and peptidomimetic synthesis. With its pervasive utilization in the domain of pharmaceutical research and investigation, particularly in the fields of oncology, immunology, and neuroscience, it evinces auspicious prospects for therapeutic application.

Category
ADCs Linker
Product Name
Fmoc-Gly-Gly-Gly-Gly-OH
CAS
1001202-16-9
Catalog Number
BADC-01586
Molecular Formula
C23H24N4O7
Molecular Weight
468.46
Purity
95%
Fmoc-Gly-Gly-Gly-Gly-OH

Ordering Information

Catalog Number Size Price Quantity
BADC-01586 -- $-- Inquiry
Description
Fmoc-Gly-Gly-Gly-Gly-OH is an inherent constituent within the biomedical realm. It serves as a pivotal foundational constituent in the conduction of peptide and peptidomimetic synthesis. With its pervasive utilization in the domain of pharmaceutical research and investigation, particularly in the fields of oncology, immunology, and neuroscience, it evinces auspicious prospects for therapeutic application.
Synonyms
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylglycylglycylglycine; (((9H-fluoren-9-yl)methoxy)carbonyl)glycylglycylglycylglycine
IUPAC Name
2-[[2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]acetyl]amino]acetic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)O
InChI
InChI=1S/C23H24N4O7/c28-19(24-10-20(29)26-12-22(31)32)9-25-21(30)11-27-23(33)34-13-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,18H,9-13H2,(H,24,28)(H,25,30)(H,26,29)(H,27,33)(H,31,32)
InChIKey
ZJOXACLWNQEOCP-UHFFFAOYSA-N
Density
1.367 g/cm3
Appearance
White Solid
Boiling Point
930.4±65.0 °C at 760 mmHg

Fmoc-Gly-Gly-Gly-Gly-OH, a tetrapeptide, is widely utilized in various applications in bioscience due to its versatility and stability. Here are some key applications of Fmoc-Gly-Gly-Gly-Gly-OH:

Peptide Synthesis: Fmoc-Gly-Gly-Gly-Gly-OH is frequently used as a building block in solid-phase peptide synthesis (SPPS). Its stable Fmoc (9-fluorenylmethyloxycarbonyl) protecting group allows for sequential addition of amino acids, facilitating the creation of complex peptides and proteins. This compound enhances the efficiency and accuracy of synthetic procedures.

Biomaterial Development: Fmoc-Gly-Gly-Gly-Gly-OH is employed in the development of novel biomaterials, including hydrogels and self-assembling peptide scaffolds. These materials are used in tissue engineering and regenerative medicine to provide structural support for cell growth and differentiation. The tetrapeptide’s ability to form stable hydrogels makes it a valuable tool for creating biocompatible materials.

Drug Delivery Systems: This peptide can be integrated into drug delivery systems to improve the solubility and stability of therapeutic agents. By conjugating drugs with Fmoc-Gly-Gly-Gly-Gly-OH, researchers can enhance drug delivery efficiency and control the release rate. This application is particularly beneficial in designing targeted drug delivery mechanisms for precision medicine.

Bioconjugation Studies: Fmoc-Gly-Gly-Gly-Gly-OH is utilized in bioconjugation techniques to attach various biomolecules, such as fluorescent dyes or biotin, to proteins or other peptides. This process is essential for creating molecular probes and diagnostic tools. The tetrapeptide serves as a linker, ensuring that the conjugated molecules retain their functional properties.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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