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Fmoc-Gly-Gly-allyl propionate is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01815 | -- | $-- | Inquiry |
Fmoc-Gly-Gly-allyl propionate, a versatile chemical compound, is utilized in peptide synthesis and various biochemical applications. Here are four key applications of Fmoc-Gly-Gly-allyl propionate:
Solid-Phase Peptide Synthesis (SPPS): A cornerstone in peptide synthesis, Fmoc-Gly-Gly-allyl propionate plays a pivotal role in solid-phase peptide synthesis by introducing specific dipeptides into developing peptide chains. Its Fmoc protecting group enables precise deprotection under gentle conditions, ensuring the meticulous assembly of peptides with targeted sequences and unique properties.
Proteomics Research: In the dynamic realm of proteomics, Fmoc-Gly-Gly-allyl propionate serves as a catalyst for creating modified peptides tailored for investigating protein interactions and functions. These altered peptides act as potent probes or inhibitors, unraveling intricate protein signaling pathways essential for deciphering disease mechanisms and pinpointing potential therapeutic targets.
Drug Development: At the forefront of pharmaceutical innovation, Fmoc-Gly-Gly-allyl propionate plays a pivotal role in the development and synthesis of peptide-based drugs. By integrating this compound, researchers can optimize the stability, solubility, and bioactivity of therapeutic peptides, enhancing their efficacy and specificity.
Bioconjugation: In bioconjugation, Fmoc-Gly-Gly-allyl propionate emerges as a key player in linking peptides to diverse biomolecules such as antibodies or nucleic acids. This harmonious fusion generates multifunctional compounds with a myriad of biological activities, crucial for diagnostic assays, targeted drug delivery, and cutting-edge therapeutic interventions.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
