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Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01119 | -- | $-- | Inquiry |
Fmoc-Gly-Gly-OH, also known as fluorenylmethyloxycarbonyl-glycyl-glycine, plays a pivotal role in peptide synthesis and biochemistry. Here are four key applications of Fmoc-Gly-Gly-OH:
Peptide Synthesis: Serving as a fundamental component in the construction of larger peptides and proteins, Fmoc-Gly-Gly-OH features an Fmoc protection group that can be effortlessly removed under mild conditions, facilitating the gradual assembly of intricate peptides. This versatility renders it indispensable for the tailored production of peptides for both research and therapeutic endeavors, enabling precision in peptide design.
Drug Development: In the realm of pharmaceutical innovation, Fmoc-Gly-Gly-OH emerges as a cornerstone for crafting peptide-based drugs and therapeutics. By integrating this dipeptide into peptide structures, researchers can engineer drugs with targeted biological functions and enhanced stability. This strategic approach aids in the creation of groundbreaking medications for a diverse array of ailments, spanning from cancers to metabolic disorders.
Structural Biology: Delving into the complexities of protein folding and structure elucidation, scientists leverage Fmoc-Gly-Gly-OH in their investigations. By synthesizing peptides incorporating Fmoc-Gly-Gly motifs, researchers can probe the significance of specific residues in protein stability and functionality, unraveling the intricate mechanisms underpinning various diseases and refining the development of therapeutic proteins with improved efficacy.
Bioconjugation: The versatile nature of Fmoc-Gly-Gly-OH extends to bioconjugation applications, wherein peptides are conjugated to diverse molecules such as fluorophores, biotin, or antibodies. This technique facilitates the exploration of molecular interactions and aids in the creation of diagnostic tools vital for biomedical research. Bioconjugates crafted using Fmoc-Gly-Gly-OH find widespread utility in assays and imaging methodologies, offering insights into and quantifying biological processes with precision and clarity.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
