Name: [2-(Fmoc-amino)acetamido]-acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

1-(9H-Fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid

IUPAC Name

2-[[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]methoxy]acetic acid

Canonical SMILES

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(=O)NCOCC(=O)O

InChI

InChI=1S/C20H20N2O6/c23-18(22-12-27-11-19(24)25)9-21-20(26)28-10-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,21,26)(H,22,23)(H,24,25)

InChIKey

LIBCNUNKCWYZAX-UHFFFAOYSA-N

[2-(Fmoc-amino)acetamido]-acid, a chemical compound widely utilized in peptide synthesis and biochemical research, serves as a versatile tool in various applications. Here are four key applications portrayed with high perplexity and burstiness:

Solid-Phase Peptide Synthesis: Integral to solid-phase peptide synthesis (SPPS), [2-(Fmoc-amino)acetamido]-acid acts as an essential amino acid building block. The Fmoc (Fluorenylmethyloxycarbonyl) group shields the amino group throughout synthesis, enabling the meticulous stepwise construction of peptides with precise sequence control. This process facilitates the production of peptides for diverse research and therapeutic endeavors, showcasing the compound's significance in peptide assembly.

Study of Peptide-Protein Interactions: Delving into the intricate realm of peptide-protein interactions, [2-(Fmoc-amino)acetamido]-acid plays a pivotal role in unraveling the complexities of biological processes and drug development. By integrating this compound into peptide sequences, researchers explore binding affinities and functional roles of peptides within intricate biological systems. This exploration aids in the crafting of peptide-based inhibitors and modulators, illustrating the compound's importance in understanding molecular interactions.

Development of Modified Peptides: Researchers harness the potential of [2-(Fmoc-amino)acetamido]-acid to craft peptides with tailored modifications, including the incorporation of non-natural amino acids. These modified peptides serve as valuable tools for investigating protein functions, designing novel therapeutics, and creating peptide-based biomaterials. The compound's adaptability in modification studies enhances the grasp and application of peptides across various disciplines, showcasing its versatility in peptide modification endeavors.

Bioconjugation Techniques: Embracing bioconjugation techniques, [2-(Fmoc-amino)acetamido]-acid acts as a crucial component for linking peptides and other biomolecules to diverse surfaces, dyes, or functional groups. This process enables the examination of peptide localization, activity, and interactions within intricate biological settings. Bioconjugates formed using this compound find utility in imaging, diagnostics, and targeted drug delivery applications, underscoring its significance in bioconjugation strategies.