Name: (2S,3S)-H-Abu(3-N3)-OH hydrochloride
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Synonyms

(2S,3S)-2-amino-3-azidobutanoic acid hydrochloride; H-Abu(3-N3).HCl (2S,3S); (2S,3S)-H-Abu(3-N3) HCl; Butanoic acid, 2-amino-3-azido-, hydrochloride (1:1), (2S,3S)-; H-Abu(3-N3)-OH HCl (2S,3S)

IUPAC Name

(2S,3S)-2-amino-3-azidobutanoic acid;hydrochloride

Canonical SMILES

C[C@@H]([C@@H](C(=O)O)N)N=[N+]=[N-].Cl

InChI

InChI=1S/C4H8N4O2.ClH/c1-2(7-8-6)3(5)4(9)10;/h2-3H,5H2,1H3,(H,9,10);1H/t2-,3-;/m0./s1

InChIKey

MWINUACJIVWJPZ-GVOALSEPSA-N

Storage

Store at 2-8 °C

(2S,3S)-H-Abu(3-N3)-OH (Hydrochloride) is a synthetic amino acid derivative utilized in various biochemical research applications. Here are some key applications of (2S,3S)-H-Abu(3-N3)-OH (hydrochloride):

Peptide Synthesis: This compound is commonly used in peptide synthesis due to its azide functional group, which facilitates click chemistry reactions. Researchers employ it to introduce specific modifications in peptides, aiding in the study of protein interactions and functions. Its versatility makes it a valuable tool in designing and synthesizing complex peptide structures.

Drug Development: (2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is instrumental in the development of new pharmaceuticals. Its incorporation into drug candidates allows for the exploration of structure-activity relationships and optimization of therapeutic properties. By enabling precise modifications, this compound helps in improving drug efficacy and reducing side effects.

Bioconjugation: In bioconjugation studies, (2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is used to attach bioactive molecules to proteins, nucleic acids, or other biomolecules. Through click chemistry, researchers can create stable and specific linkages, facilitating the development of targeted delivery systems and diagnostic tools. This application is crucial for advancing personalized medicine approaches.

Protein Engineering: This synthetic amino acid derivative is also employed in protein engineering to study protein structure and function. By incorporating (2S,3S)-H-Abu(3-N3)-OH into proteins, scientists can introduce site-specific mutations or labels, enabling detailed analysis of protein dynamics. This aids in understanding protein mechanisms and in designing proteins with novel functions.