N-Succinimidyl 3-(Bromoacetamido)propionate - CAS 57159-62-3

N-Succinimidyl 3-(Bromoacetamido)propionate - CAS 57159-62-3 Catalog number: BADC-01139

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N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

General Information

Category
ADCs Linker
Product Name
N-Succinimidyl 3-(Bromoacetamido)propionate
CAS
57159-62-3
Catalog Number
BADC-01139
Molecular Formula
C9H11BrN2O5
Molecular Weight
307.10 g/mol

Chemical Structure

  • N-Succinimidyl 3-(Bromoacetamido)propionate
Purity
>99.3%
Appearance
Off-white to white waxy solid
Synonyms
2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate; Succinimidyl-3-(bromoacetamido)propionate; 3-(2-bromoacetamido)propanoic acid NHS ester
Solubility
10 mM in DMSO
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Shelf Life
-20℃ 3 years powder; -80℃ 2 years in solvent
Shipping
Room temperature
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCNC(=O)CBr
InChI Key
WGMMKWFUXPMTRW-UHFFFAOYSA-N
InChI
InChI=1S/C9H11BrN2O5/c10-5-6(13)11-4-3-9(16)17-12-7(14)1-2-8(12)15/h1-5H2,(H,11,13)
Form
Solid

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Historical Records: Harmaline | Methyltetrazine-PEG4-oxyamine | Azido-PEG5-acid | MAL-Tri-EG-Osu | Pinocembrin | N-Boc-N-bis(PEG4-OH) | 2,5-dioxopyrrolidin-1-yl 3-(2-(2-(2-(cyclooct-2-ynyloxy)acetamido)ethoxy)ethoxy)propanoate | DBCO-NHCO-S-S-NHS ester | Mal-PEG3-C1-NHS ester | MC-Gly-Gly-Phe | N-Succinimidyl 3-(Bromoacetamido)propionate
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