Alloc-Val-Ala-PAB-OH - CAS 1343407-91-9

Alloc-Val-Ala-PAB-OH - CAS 1343407-91-9 Catalog number: BADC-01438

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Alloc-Val-Ala-PAB-OH is a peptide linker with a terminal Alloc protecting group. The peptide chain can act as a cleavable linker in drug design, such as in antibody drug conjugates (ADC).

Category
ADCs Linker
Product Name
Alloc-Val-Ala-PAB-OH
CAS
1343407-91-9
Catalog Number
BADC-01438
Molecular Formula
C19H27N3O5
Molecular Weight
377.43
Alloc-Val-Ala-PAB-OH

Ordering Information

Catalog Number Size Price Quantity
BADC-01438 250 mg $398 Inquiry
Description
Alloc-Val-Ala-PAB-OH is a peptide linker with a terminal Alloc protecting group. The peptide chain can act as a cleavable linker in drug design, such as in antibody drug conjugates (ADC).
Synonyms
Allyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate; N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide; N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide
IUPAC Name
prop-2-enyl N-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
Canonical SMILES
CC(C)C(C(=O)NC(C)C(=O)NC1=CC=C(C=C1)CO)NC(=O)OCC=C
InChI
InChI=1S/C19H27N3O5/c1-5-10-27-19(26)22-16(12(2)3)18(25)20-13(4)17(24)21-15-8-6-14(11-23)7-9-15/h5-9,12-13,16,23H,1,10-11H2,2-4H3,(H,20,25)(H,21,24)(H,22,26)/t13-,16-/m0/s1
InChIKey
LVLAVLCLIPDFJK-BBRMVZONSA-N
Density
1.194±0.06 g/cm3
Melting Point
227°C
Appearance
White Solid
Storage
Store at -20°C
Boiling Point
660.3±55.0 °C at 760 mmHg

ALLOC-L-VAL-L-ALA-PABOH, also known as Alloc-Val-Ala-PABOH, is a versatile peptide with diverse applications in biochemical and pharmaceutical fields. Explore four key applications of ALLOC-L-VAL-L-ALA-PABOH presented with high perplexity and burstiness:

Cell-Penetrating Assays: Delving into the realm of cell-penetrating assays, researchers harness the potential of ALLOC-L-VAL-L-ALA-PABOH to investigate the intricate transport mechanisms of peptides and proteins across cellular membranes. By conjugating with a fluorescent marker, scientists can meticulously track the peptide's intracellular journey, evaluating its delivery efficacy with precision. This application sparks innovation in the realm of drug delivery systems, paving the way for novel approaches in therapeutic strategies.

Protease Assays: Unveiling the dynamic world of protease assays, ALLOC-L-VAL-L-ALA-PABOH emerges as a pivotal substrate for assessing the activity of specific proteases. Upon enzymatic cleavage, this substrate triggers a discernible signal, be it fluorescence or a colorimetric shift. This distinctive feature enables researchers to quantitatively analyze protease kinetics, shedding light on enzyme functionalities and facilitating inhibitor screening processes with depth and complexity.

Peptide Synthesis: Embarking on a journey through peptide synthesis, ALLOC-L-VAL-L-ALA-PABOH plays a crucial role as a foundational building block in solid-phase peptide synthesis. Its incorporation sets the stage for the meticulous assembly of intricate peptide chains in a stepwise manner, ensuring high specificity and yield. This application stands as a cornerstone in the production of synthetic peptides for a myriad of purposes, spanning research endeavors, therapeutic innovations, and diagnostic advancements.

Drug Development: Navigating the landscape of drug development, ALLOC-L-VAL-L-ALA-PABOH emerges as a potent tool in the creation of prodrug conjugates tailored to enhance pharmacokinetic properties. Through strategic linkage with therapeutic peptides or small molecules, researchers elevate drug stability, solubility, and targeted delivery potential.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Alloc-Val-Ala-PAB-OH
Why Choose BOC Sciences?

Customer Support

Providing excellent 24/7 customer service and support

Project Management

Offering 100% high-quality services at all stages

Quality Assurance

Ensuring the quality and reliability of products or services

Global Delivery

Ensuring timely delivery of products worldwide

Questions & Comments
Verification code
Send Inquiry
Verification code
Resources & Supports
Inquiry Basket