Name: Alloc-Val-Ala-PAB-OH
Brand: BOC Sciences
Price: 398 USD
Availability: MadeToOrder

Synonyms

Allyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate; N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide; N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide

IUPAC Name

prop-2-enyl N-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate

Canonical SMILES

CC(C)C(C(=O)NC(C)C(=O)NC1=CC=C(C=C1)CO)NC(=O)OCC=C

InChI

InChI=1S/C19H27N3O5/c1-5-10-27-19(26)22-16(12(2)3)18(25)20-13(4)17(24)21-15-8-6-14(11-23)7-9-15/h5-9,12-13,16,23H,1,10-11H2,2-4H3,(H,20,25)(H,21,24)(H,22,26)/t13-,16-/m0/s1

InChIKey

LVLAVLCLIPDFJK-BBRMVZONSA-N

Density

1.194±0.06 g/cm3

Melting Point

227°C

Appearance

White Solid

Storage

Store at -20°C

Boiling Point

660.3±55.0 °C at 760 mmHg

ALLOC-L-VAL-L-ALA-PABOH, also known as Alloc-Val-Ala-PABOH, is a versatile peptide with diverse applications in biochemical and pharmaceutical fields. Explore four key applications of ALLOC-L-VAL-L-ALA-PABOH presented with high perplexity and burstiness:

Cell-Penetrating Assays: Delving into the realm of cell-penetrating assays, researchers harness the potential of ALLOC-L-VAL-L-ALA-PABOH to investigate the intricate transport mechanisms of peptides and proteins across cellular membranes. By conjugating with a fluorescent marker, scientists can meticulously track the peptide's intracellular journey, evaluating its delivery efficacy with precision. This application sparks innovation in the realm of drug delivery systems, paving the way for novel approaches in therapeutic strategies.

Protease Assays: Unveiling the dynamic world of protease assays, ALLOC-L-VAL-L-ALA-PABOH emerges as a pivotal substrate for assessing the activity of specific proteases. Upon enzymatic cleavage, this substrate triggers a discernible signal, be it fluorescence or a colorimetric shift. This distinctive feature enables researchers to quantitatively analyze protease kinetics, shedding light on enzyme functionalities and facilitating inhibitor screening processes with depth and complexity.

Peptide Synthesis: Embarking on a journey through peptide synthesis, ALLOC-L-VAL-L-ALA-PABOH plays a crucial role as a foundational building block in solid-phase peptide synthesis. Its incorporation sets the stage for the meticulous assembly of intricate peptide chains in a stepwise manner, ensuring high specificity and yield. This application stands as a cornerstone in the production of synthetic peptides for a myriad of purposes, spanning research endeavors, therapeutic innovations, and diagnostic advancements.

Drug Development: Navigating the landscape of drug development, ALLOC-L-VAL-L-ALA-PABOH emerges as a potent tool in the creation of prodrug conjugates tailored to enhance pharmacokinetic properties. Through strategic linkage with therapeutic peptides or small molecules, researchers elevate drug stability, solubility, and targeted delivery potential.