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DBCO-sulfo-NHS Ester

  CAS No.: 1400191-52-7   Cat No.: BADC-00945   Purity: >98.0% 4.5  

DBCO-sulfo-NHS Ester is a water-soluble ADC linker with DBCO for copper-free click chemistry and NHS ester for efficient amine coupling, optimizing antibody-payload conjugation stability and hydrophilicity.

DBCO-sulfo-NHS Ester

Structure of 1400191-52-7

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Category
ADC Linker
Molecular Formula
C25H21N2NaO8S
Molecular Weight
532.50
Shipping
Room temperature
Shipping
Store at -20°C

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
6-oxo-6-(dibenzo[b,f]azacyclooct-4-yn-1-yl)-caproic acid sulfo-N-hydroxysuccinimide ester, sodium salt; DBCO-Sulfo-NHS ester (sodium)
IUPAC Name
Canonical SMILES
C1C(C(=O)N(C1=O)OC(=O)CCCCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42)S(=O)(=O)[O-].[Na+]
InChI
InChI=1S/C25H22N2O8S.Na/c28-22(11-5-6-12-24(30)35-27-23(29)15-21(25(27)31)36(32,33)34)26-16-19-9-2-1-7-17(19)13-14-18-8-3-4-10-20(18)26;/h1-4,7-10,21H,5-6,11-12,15-16H2,(H,32,33,34);/q;+1/p-1
InChIKey
QXKHPYSXPCJSPR-UHFFFAOYSA-M
Solubility
10 mm in DMSO
Shelf Life
≥ 2 years
Shipping
Room temperature
Storage
Store at -20°C

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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