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Boc-Dap-NE

  CAS No.: 160800-65-7   Cat No.: BADC-00973   Purity: >98.0% 4.5  

Boc-Dap-NE is a protected amino-functionalized ADC linker intermediate used in the synthesis of site-specific antibody conjugates for improved drug delivery and stability.

Boc-Dap-NE

Structure of 160800-65-7

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Category
ADC Linker
Molecular Formula
C23H36N2O5
Molecular Weight
420.54
Shipping
Room temperature
Storage
-20°C

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
(S)-Tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
IUPAC Name
tert-butyl (2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidine-1-carboxylate
Canonical SMILES
CC(C(C1CCCN1C(=O)OC(C)(C)C)OC)C(=O)NC(C)C(C2=CC=CC=C2)O
InChI
InChI=1S/C23H36N2O5/c1-15(21(27)24-16(2)19(26)17-11-8-7-9-12-17)20(29-6)18-13-10-14-25(18)22(28)30-23(3,4)5/h7-9,11-12,15-16,18-20,26H,10,13-14H2,1-6H3,(H,24,27)/t15-,16-,18+,19-,20-/m1/s1
InChIKey
XJDVGABQIFOWFC-SCQOQHIRSA-N
Solubility
10 mm in DMSO
Appearance
Solid
Shelf Life
-20°C 3 years powder; -80°C 2 years in solvent
Shipping
Room temperature
Storage
-20°C
Form
Solid

Boc-Dap-NE, a versatile chemical compound utilized in peptide synthesis and various biochemical applications, plays a pivotal role in multiple domains. Here are four key applications of Boc-Dap-NE presented with a high degree of perplexity and burstiness:

Peptide Synthesis: Serving as a crucial protecting group, Boc-Dap-NE finds extensive use in peptide synthesis, ensuring the preservation of amino functional groups throughout peptide bond formation. This safeguarding mechanism guarantees the precision in synthesizing intricate peptide sequences, empowering researchers to craft complex peptides and proteins with impeccable precision and purity.

Drug Development: In the realm of drug discovery, Boc-Dap-NE emerges as a vital component in synthesizing peptide-based drugs with tailored sequences essential for therapeutic efficacy. This compound facilitates the production of peptides designed to function as enzyme inhibitors or receptor agonists, opening doors to potential breakthroughs in new drug development pathways.

Bioconjugation: Within bioconjugation processes, Boc-Dap-NE plays a critical role in linking peptides to various molecules like fluorescent dyes or antibodies, a pivotal step in developing diagnostic tools and targeted therapeutics. By leveraging Boc-Dap-NE, researchers can ensure the selective and efficient attachment of peptides to these functional molecules.

Protein Engineering: In the domain of protein engineering, Boc-Dap-NE is utilized to incorporate modified amino acids into proteins, thereby altering crucial properties such as stability, activity, or binding affinity. This transformative modification capability enables scientists to engineer proteins with enhanced characteristics tailored for diverse industrial and therapeutic purposes, showcasing the versatility and potential of Boc-Dap-NE in advancing protein engineering endeavors.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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