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Boc-D-Lys(N3)-OH CHA is a click chemistry reagent containing an azide group.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01761 | -- | $-- | Inquiry |
Boc-D-Lys(N3)-OH, a specialized amino acid derivative, plays a pivotal role in peptide synthesis and bioconjugation.
Peptide Synthesis: Widely employed in solid-phase peptide synthesis, Boc-D-Lys(N3)-OH facilitates the integration of azide-functionalized lysine residues into peptides. This strategic modification sets the stage for the subsequent attachment of diverse chemical groups via click chemistry reactions, culminating in the construction of intricate peptide-based structures essential for both research and therapeutic endeavors.
Bioconjugation: The azide group inherent in Boc-D-Lys(N3)-OH streamlines efficient conjugation with alkyne-containing molecules through copper-catalyzed azide-alkyne cycloaddition (CuAAC). This versatile technique is harnessed to label peptides with fluorescent dyes, biotin, or other functional moieties, yielding bioconjugates that find indispensable utility in diagnostic assays, imaging modalities, and targeted therapeutic interventions.
Protein Engineering: Introducing Boc-D-Lys(N3)-OH into proteins enables precise site-specific modifications and functionalizations. Researchers leverage this capability to engineer proteins endowed with unique chemical traits, enabling detailed investigations into protein-protein interactions and the design of innovative protein-based pharmaceuticals. This approach empowers researchers with meticulous control over protein architecture and function.
Drug Delivery Systems: Leveraging Boc-D-Lys(N3)-OH, researchers craft tailored drug delivery systems by selectively attaching therapeutic agents to peptides or proteins. This bespoke approach ensures targeted delivery and controlled release of drugs, enhancing therapeutic efficacy while mitigating potential side effects. Such meticulously designed delivery systems play a critical role in advancing biomedical treatments to new heights of precision and effectiveness.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
