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Dov-Val-Dil-OtBu

  CAS No.: 120205-53-0   Cat No.: BADC-01574 4.5  

Dov-Val-Dil-OtBu is a remarkable biomedicine chemical in the arena of cardiovascular therapeutic interventions. Positioned as an indispensable inhibitor targeting the exquisitely intricate enzyme network, it propels precision in blood pressure modulation and orchestrates the harmonious functioning of the heart.

Dov-Val-Dil-OtBu

Structure of 120205-53-0

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ADC Linker
Molecular Formula
C26H51N3O5
Molecular Weight
485.70

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-(1,1-dimethylethoxy)-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; (3R,4S,5S)-tert-butyl 4-((S)-2-((S)-2-(dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoate
IUPAC Name
tert-butyl (3R,4S,5S)-4-[[(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methoxy-5-methylheptanoate
Canonical SMILES
CCC(C)C(C(CC(=O)OC(C)(C)C)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C
InChI
InChI=1S/C26H51N3O5/c1-14-18(6)23(19(33-13)15-20(30)34-26(7,8)9)29(12)25(32)21(16(2)3)27-24(31)22(17(4)5)28(10)11/h16-19,21-23H,14-15H2,1-13H3,(H,27,31)/t18-,19+,21-,22-,23-/m0/s1
InChIKey
MAYJVBBZJLABTA-HUMDQVGNSA-N
Appearance
White Solid

Dov-Val-Dil-OtBu, a chemical compound utilized in bioscience research, plays a pivotal role in peptide synthesis and drug development. Here are four key applications of Dov-Val-Dil-OtBu:

Peptide Synthesis: Serving as a critical intermediate in the creation of intricate peptides, Dov-Val-Dil-OtBu's stable, protected form renders it ideal for solid-phase peptide synthesis. This allows for its seamless integration into burgeoning peptide chains, streamlining the production of highly pure and precise peptides with high accuracy.

Drug Development: Positioned as a cornerstone in the pharmaceutical landscape, Dov-Val-Dil-OtBu finds extensive utility in crafting peptide-based therapeutic agents. By furnishing a sturdy building block, this compound assists researchers in crafting and engineering peptide drugs endowed with heightened stability and enhanced bioavailability. The implications extend to treating afflictions like cancer, diabetes, and infectious diseases.

Protein Engineering: In the avant-garde domain of protein engineering, Dov-Val-Dil-OtBu emerges as a catalyst for introducing targeted modifications into proteins. Its incorporation into protein sequences facilitates the exploration of protein-protein interactions, folding dynamics, and structural stability. This deep dive into protein function is instrumental in sculpting novel proteins with far-reaching applications in both therapeutic realms and industrial landscapes.

Bioconjugation: Expanding the frontiers of bioconjugation techniques, Dov-Val-Dil-OtBu serves as a linchpin in linking peptides or proteins to diverse molecules such as fluorescent markers, pharmaceuticals, or nanoparticles. This convergence spawns multifaceted bioconjugates that elevate the efficacy of imaging modalities, diagnostics, and precision-targeted drug delivery mechanisms.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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