Inquiry Basket
CAS No.: 796073-55-7
Cat No.: BADC-01161
Purity: >99.3%
4.5 
4-Methyl-4-(methyldisulfanyl)pentanoic acid is a disulfide-containing ADC linker enabling selective cleavage and drug release. Its reactive acid group supports conjugation to antibodies for targeted cancer therapy applications.
Structure of 796073-55-7
* For research and manufacturing use only. We do not sell to patients.
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | $-- | In stock |
Looking for different specifications? Click to request a custom quote!
Capabilities & Facilities
Popular Publications Citing BOC Sciences Products
4-Methyl-4-(methyldisulfanyl)pentanoic acid, a specialized chemical compound, plays a pivotal role in biochemistry and pharmaceuticals. Here are four key applications presented with a high degree of perplexity and burstiness:
Enzyme Inhibition Studies: Delving into biochemical research, this compound emerges as a key player in the realm of enzyme inhibition dynamics. It interacts intricately with specific enzyme active sites, shedding light on the intricate mechanisms governing enzyme regulation and inhibition. This knowledge forms the bedrock for the development of groundbreaking drugs targeting disease-associated enzymes, propelling advancements in therapeutic interventions.
Drug Development: Positioned on the forefront of pharmaceutical research, 4-Methyl-4-(methyldisulfanyl)pentanoic acid takes center stage as a lead compound with immense potential in the creation of novel therapeutic agents. Its unique chemical structure serves as a canvas for modifications aimed at optimizing pharmacokinetic and pharmacodynamic properties. Researchers harness its capabilities to pioneer new medications with heightened efficacy and diminished side effects, shaping the landscape of modern medicine.
Protein Modification: Within the realm of protein chemistry, this compound emerges as a catalyst for introducing disulfide bonds, thereby sculpting protein structure and function with finesse. This capability proves invaluable in the exploration of protein stability and folding dynamics across diverse conditions. Such modifications also find application in the realm of biopharmaceutical design, paving the way for enhanced stability and activity, pushing the boundaries of protein engineering.
Industrial Biotechnology: Embracing the realm of industrial biotechnology, 4-Methyl-4-(methyldisulfanyl)pentanoic acid emerges as a powerhouse in the synthesis of specialty chemicals and polymers. Its reactivity becomes a cornerstone in the creation of chemical intermediates crucial for industrial processes. This application underpins the production of advanced materials tailored to meet the specific requirements of diverse technological applications, driving innovation and progress in industrial sectors.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-00963 | 4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid | 1537891-69-2 |
What is 4-Methyl-4-(methyldisulfanyl)pentanoic acid used for in ADCs?
4-Methyl-4-(methyldisulfanyl)pentanoic acid is utilized as a cleavable linker in antibody-drug conjugates, facilitating controlled release of cytotoxic payloads within target cells while maintaining plasma stability.
1/2/2017
We would like to know how 4-Methyl-4-(methyldisulfanyl)pentanoic acid enhances ADC stability.
The disulfide bond in 4-Methyl-4-(methyldisulfanyl)pentanoic acid provides stability in systemic circulation and ensures selective cleavage in reducing intracellular environments, minimizing off-target toxicity.
12/4/2019
Dear BOC Sciences, which payloads are compatible with 4-Methyl-4-(methyldisulfanyl)pentanoic acid?
This linker is compatible with a range of small molecule cytotoxins, including auristatins and maytansinoids, enabling conjugation through thiol or amine chemistry without affecting antibody integrity.
5/4/2019
Good morning! What considerations should be made when using 4-Methyl-4-(methyldisulfanyl)pentanoic acid in ADC design?
Considerations include redox potential of target cells, linker length optimization for steric accessibility, and evaluation of payload release kinetics to achieve desired therapeutic index.
1/1/2018
Dear team, what handling precautions are recommended for 4-Methyl-4-(methyldisulfanyl)pentanoic acid?
4-Methyl-4-(methyldisulfanyl)pentanoic acid should be stored at -20°C in a dry environment to prevent oxidation. Handling should minimize moisture and light exposure. Using aliquots is advised to maintain disulfide functionality, ensuring reproducible performance in linker synthesis and bioconjugation reactions.
1/12/2018
— Dr. Robert Evans, Protein Chemist (USA)
4-Methyl-4-(methyldisulfanyl)pentanoic acid linker offered excellent disulfide stability and minimal side reactions.
5/4/2019
— Prof. Elena Russo, Medicinal Chemist (Italy)
The disulfide functionality facilitated controlled intracellular payload release. Very reliable.
1/12/2018
— Dr. Stefan Weber, Bioconjugation Specialist (Germany)
BOC Sciences provided 4-Methyl-4-(methyldisulfanyl)pentanoic acid with high purity and consistent batch quality.
1/1/2018
— Ms. Laura Smith, R&D Manager (UK)
Using this disulfide linker, we obtained reproducible conjugation and efficient payload release.
1/2/2017
— Dr. Ingrid Jensen, ADC Project Lead (Denmark)
Excellent technical support and documentation accompanied 4-Methyl-4-(methyldisulfanyl)pentanoic acid.
— Mr. Felix Martin, Senior Scientist (France)
The linker’s stability and solubility made high-throughput ADC conjugation straightforward.
12/5/2019
4-Methyl-4-(methyldisulfanyl)pentanoic acid
Required fields are marked with *
4-Methyl-4-(methyldisulfanyl)pentanoic acid
Required fields are marked with *
Contact our experts today for pricing and comprehensive details on our ADC offerings.
From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.
Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.
Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.
