Acid-propionylamino-Val-Cit-OH is a cleavable ADC linker with propionylated amino group and valine-citrulline dipeptide, designed for enzymatic payload release in antibody-drug conjugates.
Structure of 2098907-84-5
* For research and manufacturing use only. We do not sell to patients.
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Capabilities & Facilities
Acid-propionylamino-Val-Cit-OH, a synthetic compound with versatile therapeutic uses, plays a pivotal role in various applications. Explore its key applications with a high degree of perplexity and burstiness:
Antibody-Drug Conjugates (ADCs): Dive into the realm of antibody-drug conjugates where Acid-propionylamino-Val-Cit-OH serves as a crucial linker, ensuring the stability of the conjugate in the bloodstream while orchestrating the precise release of cytotoxic drugs at target sites. This innovative technology not only enhances the therapeutic index of cancer treatments but also minimizes undesirable side effects, amplifying treatment efficacy to combat this formidable disease.
Peptide-based Drug Design: Journey into the realm of precision medicine with Acid-propionylamino-Val-Cit-OH as a cornerstone in synthesizing peptide-based drugs tailored for targeted therapeutic actions. This compound plays a pivotal role in enhancing the solubility and stability of peptide drugs, allowing designers to fine-tune pharmacokinetic and pharmacodynamic properties, optimizing the performance of these therapeutic agents with surgical precision.
Bioconjugation Reactions: Unravel the intricacies of bioconjugation reactions where Acid-propionylamino-Val-Cit-OH shines as a key player in attaching biomolecules such as peptides, proteins, and antibodies to diverse substrates. This cutting-edge approach fuels the creation of novel diagnostic and therapeutic tools, empowering researchers to craft highly specific probes for imaging and targeted therapies, pushing the boundaries of personalized medicine and precision healthcare.
Proteomics Studies: Embark on a journey through the world of proteomics where Acid-propionylamino-Val-Cit-OH plays a crucial role in studying protein interactions and functions. By aiding in labeling and detecting specific proteins within complex biological samples, this compound unravels new biomarkers and unveils the intricate mechanisms underlying various diseases at the molecular level, paving the way for breakthroughs in personalized medicine and targeted therapies.
Catalog | Product Name | CAS | Inquiry |
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BADC-00969 | Val-Cit | 159858-33-0 | |
BADC-01279 | MC(C5)-Val-Cit | 2504147-59-3 | |
BADC-01178 | Boc-Val-Cit-OH | 870487-08-4 | |
BADC-01255 | DBCO-Val-Cit-OH |
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