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| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01018 | -- | $-- | Inquiry |
Mc-Val-Ala-PAB, a key linker molecule in drug delivery and bioconjugation, boasts diverse applications across various domains.
Targeted Drug Delivery: Central to antibody-drug conjugate (ADC) development, Mc-Val-Ala-PAB linkers serve as essential components for precisely ferrying chemotherapeutic agents to cancerous cells. By maintaining drug dormancy until reaching the target site, these linkers minimize adverse effects and optimize treatment efficacy.
Prodrug Development: In the realm of pharmacology, Mc-Val-Ala-PAB linkers are pivotal for designing prodrugs that activate under specific conditions, enhancing drug stability and enabling targeted activation within the body. This innovative approach enables concentrated drug delivery to diseased tissues while minimizing systemic toxicity, reshaping conventional drug administration practices for better outcomes.
Bioconjugation Techniques: Researchers utilize Mc-Val-Ala-PAB linkers in bioconjugation efforts to attach therapeutic agents like proteins and oligonucleotides to specific biomolecules. This strategic binding technique is essential for crafting precision-targeted therapeutics and diagnostics, enhancing bioactive compound bioavailability and accuracy through stable and specific couplings.
Peptide-based Drug Design: Mc-Val-Ala-PAB serves as a cornerstone in the peptide-based drug design landscape, facilitating the conjugation of peptides with small molecules or larger proteins to improve their pharmacokinetic properties. These linkages enhance the stability and delivery efficiency of peptide drugs, boosting their effectiveness in combating diseases and propelling advancements in personalized medicine.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
