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Maleimide-NH-PEG10-CH2CH2COONHS Ester is a versatile bioactive ester that can be used to develop targeted drug delivery systems. It acts as a linker to bind drugs or imaging agents to targeting molecules, facilitating their selective delivery to specific cells or tissues. In addition, it can be used in the development and synthesis of cancer treatment drugs.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00440 | -- | $-- | Inquiry |
Maleimide-NH-PEG10-CH2CH2COONHS Ester, a versatile chemical reagent, finds wide applications in bioconjugation and surface modification.
Protein Conjugation: Maleimide-NH-PEG10-CH2CH2COONHS Ester plays a crucial role in conjugating proteins, peptides, or antibodies with various molecules or interfaces. The maleimide group selectively reacts with thiol groups on cysteine residues, forming robust thioether linkages.
Polymer Surface Modification: Delving into materials science, this compound is pivotal in altering polymer surface properties to enhance their compatibility with biological systems. The inclusion of the PEG moiety confers hydrophilicity and diminishes protein adsorption, making it ideal for coating medical devices like stents or catheters. This modification aids in reducing immune responses and optimizing device functionality.
Drug Delivery Systems: Embark on the realm of pharmaceuticals with Maleimide-NH-PEG10-CH2CH2COONHS Ester being utilized in crafting targeted drug delivery systems by affixing therapeutic agents to carrier molecules. The ester linkage facilitates drug attachment to nanocarriers, such as liposomes or nanoparticles, enabling precise and controlled drug release. This strategy amplifies drug efficacy while minimizing off-target effects.
Biomolecule Immobilization: In the domain of biosensor technology, Maleimide-NH-PEG10-CH2CH2COONHS Ester emerges as a key player in immobilizing biomolecules onto sensor surfaces. The NHS ester group engages with amines, ensuring stable attachment of proteins, enzymes, or DNA to sensor platforms. This process guarantees sensitive and reliable detection in diverse analytical and diagnostic scenarios, underscoring its significance in advancing biotechnology.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
