Name: Bis-PEG7-acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid; HOOCCH2CH2O-PEG6-CH2CH2COOH; α,ω-Dipropionic acid hexaethylene glycol; 4,7,10,13,16,19,22-Heptaoxapentacosane-1,25-dioic acid

IUPAC Name

3-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Canonical SMILES

C(COCCOCCOCCOCCOCCOCCOCCC(=O)O)C(=O)O

InChI

InChI=1S/C18H34O11/c19-17(20)1-3-23-5-7-25-9-11-27-13-15-29-16-14-28-12-10-26-8-6-24-4-2-18(21)22/h1-16H2,(H,19,20)(H,21,22)

InChIKey

AYUREXAVZVVOJM-UHFFFAOYSA-N

Density

1.186±0.06 g/cm3

Solubility

Soluble in DMSO

PSA

139.21000

Appearance

Pale Yellow or Colorless Oily Matter

Shipping

Room temperature, or blue ice upon request.

Storage

Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

Boiling Point

572.8±50.0 °C at 760 mmHg

Form

Solid

Bis-PEG7-acid, a polyethylene glycol-based compound, is commonly utilized in bioconjugation and drug delivery. Here are four key applications of Bis-PEG7-acid presented with heightened perplexity and burstiness:

Drug Delivery: Utilizing Bis-PEG7-acid, researchers engineer biocompatible and hydrophilic drug delivery systems. By conjugating it to drugs or therapeutic agents, it enhances their solubility and stability in the bloodstream, thereby potentially boosting the efficacy and bioavailability of treatments, particularly beneficial for hydrophobic drugs.

Bioconjugation: A versatile tool in bioconjugation, Bis-PEG7-acid facilitates the linkage of biomolecules like proteins, peptides, and antibodies, maintaining their biological activity. This compound enables the creation of multifunctional bioconjugates for both research and therapeutic purposes, showcasing its value in advancing biotechnological applications.

Protein Modification: In the realm of protein modification, Bis-PEG7-acid plays a pivotal role in enhancing the pharmacokinetic properties of proteins. By conjugating polyethylene glycol chains to proteins, it can mitigate immunogenicity and prolong their circulation within the body, a critical aspect in the realm of developing protein-based therapeutics for improved patient outcomes.

Polymer Chemistry: With its unique qualities, Bis-PEG7-acid finds utility in polymer chemistry for crafting copolymers and hydrogels with tailored mechanical and chemical characteristics. These materials hold promise for diverse biomedical applications, including tissue engineering and controlled release systems, illustrating the vast potential of this compound in advancing medical technologies.