Bis-PEG8-acid - CAS 1246189-43-4

Bis-PEG8-acid - CAS 1246189-43-4 Catalog number: BADC-00907

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Bis-PEG8-acid is a PEG linker containing two terminal carboxylic acid groups. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Category
ADCs Linker
Product Name
Bis-PEG8-acid
CAS
1246189-43-4
Catalog Number
BADC-00907
Molecular Formula
C20H38O12
Molecular Weight
470.51
Bis-PEG8-acid

Ordering Information

Catalog Number Size Price Quantity
BADC-00907 -- $--
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Description
Bis-PEG8-acid is a PEG linker containing two terminal carboxylic acid groups. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms
HOOC-PEG7-CH2CH2COOH; HOOCCH2CH2O-PEG7-CH2CH2COOH; 4,7,10,13,16,19,22,25-Octaoxaoctacosanedioic acid; Bis-PEG8-COOH; 4,7,10,13,16,19,22,25-Octaoxaoctacosane-1,28-dioic Acid; Di-Acid-PEG8
IUPAC Name
3-[2-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES
C(COCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)C(=O)O
InChI
InChI=1S/C20H38O12/c21-19(22)1-3-25-5-7-27-9-11-29-13-15-31-17-18-32-16-14-30-12-10-28-8-6-26-4-2-20(23)24/h1-18H2,(H,21,22)(H,23,24)
InChIKey
IRTAMFHIULAGCS-UHFFFAOYSA-N
Density
1.179±0.06 g/cm3 (Predicted)
Solubility
Soluble in DMSO
Appearance
Pale Yellow or Colorless Oily Matter
Purity
≥95%
Shelf Life
-20℃ 3 years powder; -80℃ 2 years in solvent
Shipping
Room temperature, or blue ice upon request.
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Boiling Point
601.8±55.0°C (Predicted)
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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