bis-PEG2-endo-BCN - CAS 1476737-97-9 Catalog number: BADC-00955

Bis-PEG2-endo-BCN, a versatile bifunctional linker, finds extensive utility in bioconjugation and drug delivery realms. Here are four key applications of Bis-PEG2-endo-BCN presented with high perplexity and burstiness:

1. Targeted Drug Delivery: Bis-PEG2-endo-BCN offers a sophisticated means of directing therapeutic agents to precise cells or tissues by binding to biomolecules like antibodies. This targeted strategy minimizes off-target effects, amplifying the therapeutic potency of the drug. Its significance shines in cancer therapy, where accurate delivery to tumor cells holds paramount importance.

2. Diagnostic Imaging: Leveraging Bis-PEG2-endo-BCN, researchers can conjugate imaging agents to targeting ligands, enriching diagnostic imaging practices. This application elevates the contrast and specificity of imaging modalities such as MRI or PET scans, enabling superior visualization and early detection of diseases like cancer and cardiovascular disorders.

3. Protein-Protein Interaction Studies: Bis-PEG2-endo-BCN plays a pivotal role in probing protein-protein interactions, uniting proteins with reporter molecules. This facilitates real-time tracking of complex formation and dissociation, shedding light on protein function and signaling pathways. Unraveling these intricate interactions is indispensable for drug discovery and biochemical investigations.

4. Development of Bioconjugates: Widely embraced in bioconjugate synthesis, Bis-PEG2-endo-BCN fuels the creation of innovative constructs like antibody-drug conjugates (ADCs) and enzyme-prodrug conjugates. By tethering bioactive compounds to carriers or functional molecules, researchers craft novel therapeutics endowed with heightened stability and specificity.