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Maleimide-NH-PEG3-CH2CH2COOPFP Ester is a basic compound widely used in the biomedical field. It is an indispensable linker for coordinating the conjugation of different biomolecules, thereby accelerating the precise administration of therapeutics and diagnostics. Its widespread use in the synthesis of pioneering drug therapies and bioconjugates has led to promising clinical benefits.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-00445 | -- | $-- | Inquiry |
Maleimide-NH-PEG3-CH2CH2COOPFP Ester, a versatile chemical reagent with widespread utility in bioconjugation and surface modification across scientific and industrial domains, is explored through four key applications:
Protein Conjugation: Serving as a pivotal player in protein modification and labeling, Maleimide-NH-PEG3-CH2CH2COOPFP Ester engages in thiol-specific conjugation processes, enabling precise attachment of polymers, dyes, or biomolecules at specific protein sites through interaction with free thiols.
Surface Functionalization: This versatile ester plays a critical role in surface modification by endowing surfaces with PEGylated chains to enhance biocompatibility and curtail nonspecific binding in biosensors and medical devices. By introducing a PEG spacer, the compound establishes a hydrophilic shield that deters fouling and enhances instrument performance, ultimately advancing biomaterials and medical device technology.
Drug Delivery Systems: Maleimide-NH-PEG3-CH2CH2COOPFP Ester emerges as a linchpin in designing targeted drug delivery systems by facilitating attachment of targeting ligands or therapeutic agents to nanoparticles and liposomes. This precision-driven mechanism heightens drug efficacy, diminishes adverse effects, and holds promising implications in cancer treatment and personalized medicine, offering finely honed strategies for potent therapeutic outcomes.
Polymer Synthesis: Within polymer chemistry, this compound assumes a central role in synthesizing functionalized PEG polymers for diverse applications. By introducing reactive ester groups, researchers fashion block copolymers and hydrogels with tailored properties suitable for applications like tissue engineering and regenerative medicine. This versatility enables fine-tuning of physical and biochemical attributes of polymer-based materials, fostering the creation of bespoke materials for specific applications.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
