N-(2-(2-Ethylphenoxy)ethyl)-4-Formylbenzamide is an aldehyde-functionalized ADC linker optimized for site-specific bioorthogonal conjugation, improving antibody-drug conjugate stability and targeted drug release.
Structure of 1226394-63-3
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Applications in Medicinal Chemistry: N-(2-(2-Ethylphenoxy)ethyl)-4-Formylbenzamide is a valuable compound in the field of medicinal chemistry, primarily for its potential to serve as a scaffold for the design of bioactive molecules. The unique combination of the ethylphenoxy and formylbenzamide functional groups makes it a versatile building block for creating novel inhibitors of enzymes and receptors involved in various diseases. This compound is being explored for its ability to modulate critical biological pathways associated with cancer, inflammation, and metabolic disorders. By selectively targeting specific proteins and enzymes, N-(2-(2-Ethylphenoxy)ethyl)-4-Formylbenzamide has the potential to be developed into therapeutics with high specificity and efficacy.
Drug Delivery Applications: N-(2-(2-Ethylphenoxy)ethyl)-4-Formylbenzamide is also of interest in the field of drug delivery systems. Its chemical structure, with the ethylphenoxy group, enhances solubility and stability, which is crucial for its integration into various delivery platforms like nanoparticles, liposomes, or micelles. These systems can help improve the pharmacokinetics and bioavailability of therapeutic drugs, allowing for more controlled and targeted delivery to diseased tissues. The compound’s ability to modify drug release profiles makes it particularly useful for the treatment of localized diseases, such as cancer, where reducing systemic toxicity and enhancing drug concentration at the target site are essential for treatment success.
Enzyme Inhibition and Molecular Targeting: A critical application of N-(2-(2-Ethylphenoxy)ethyl)-4-Formylbenzamide is its potential as an enzyme inhibitor. The formylbenzamide moiety can interact with various enzymes involved in critical cellular processes, such as kinases, proteases, and other regulatory proteins. This interaction allows for the selective modulation of key pathways related to cell growth, metabolism, and apoptosis, making it a promising candidate for targeted therapies. By inhibiting specific enzymes, N-(2-(2-Ethylphenoxy)ethyl)-4-Formylbenzamide could be used to treat diseases where enzyme dysregulation plays a key role, such as cancer, cardiovascular diseases, and chronic inflammatory conditions.
Anti-inflammatory and Immune Modulation: Another significant application of N-(2-(2-Ethylphenoxy)ethyl)-4-Formylbenzamide lies in its anti-inflammatory properties. Chronic inflammation is associated with a range of diseases, including rheumatoid arthritis, inflammatory bowel disease, and autoimmune disorders. The compound has shown promise in modulating inflammatory pathways by interacting with key inflammatory mediators. By targeting specific molecules involved in immune responses, N-(2-(2-Ethylphenoxy)ethyl)-4-Formylbenzamide could help reduce inflammation and prevent tissue damage. Its use in the development of anti-inflammatory therapies could provide more effective and targeted treatments with fewer side effects compared to traditional therapies.
Catalog | Product Name | CAS | Inquiry |
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BADC-00523 | N-(2-(2-Chloroethoxy)ethyl)-4-Formylbenzamide | 1137575-49-5 | |
BADC-00531 | N-(2-(4-Fluorophenoxy)ethyl)-4-Formylbenzamide | 1225588-22-6 | |
BADC-00532 | N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide | 1225588-29-3 | |
BADC-00533 | N-(2-(2-Fluorophenoxy)ethyl)-4-Formylbenzamide | 1225705-45-2 | |
BADC-00534 | N-(2-(3-Ethylphenoxy)ethyl)-4-Formylbenzamide | 1225790-49-7 | |
BADC-00535 | N-(2-(4-Ethylphenoxy)ethyl)-4-Formylbenzamide | 1225790-59-9 | |
BADC-00536 | N-(2-(2,6-Dimethylphenoxy)ethyl)-4-Formylbenzamide | 1225936-91-3 | |
BADC-00539 | N-(2-(2-Chlorophenoxy)ethyl)-4-Formylbenzamide | 1225972-65-5 | |
BADC-00540 | N-(2-((2,3-Dihydro-1H-Inden-5-yl)oxy)ethyl)-4-Formylbenzamide | 1225979-81-6 | |
BADC-00541 | N-(2-(Benzo[d][1,3]dioxol-5-yloxy)ethyl)-4-Formylbenzamide | 1226006-03-6 |
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