N-(2-(2-Ethoxyphenoxy)ethyl)-4-Formylbenzamide is an aldehyde-bearing ADC linker designed for selective conjugation and enhanced antibody-drug conjugate stability, optimizing targeted drug delivery in cancer treatment.
Structure of 1226221-04-0
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Applications in Medicinal Chemistry: N-(2-(2-Ethoxyphenoxy)ethyl)-4-Formylbenzamide is an important compound in medicinal chemistry due to its potential for developing novel therapeutic agents. The compound features a distinctive ethoxyphenoxy group and a formylbenzamide moiety, making it a versatile scaffold for designing bioactive molecules. Researchers are exploring its use in creating selective inhibitors for various enzymes involved in critical biological processes. Its structure enables it to interact with specific molecular targets, such as kinases, receptors, or enzymes, which are often implicated in diseases like cancer, inflammation, and neurodegenerative disorders. By modifying these pathways, this compound could offer new strategies for drug development with improved specificity and efficacy.
Drug Delivery and Targeted Therapies: Another significant application of N-(2-(2-Ethoxyphenoxy)ethyl)-4-Formylbenzamide is in the field of drug delivery. The ethoxyphenoxy group enhances its solubility in both aqueous and organic environments, making it suitable for incorporation into drug delivery systems like nanoparticles or liposomes. These systems can facilitate the controlled release of therapeutic agents, ensuring that drugs are delivered directly to target tissues with minimal side effects. This compound’s ability to enhance the stability and bioavailability of drugs makes it particularly useful in cancer therapy, where precise drug targeting and reduced systemic toxicity are crucial. Its integration into nanocarriers could significantly improve the efficacy of existing drugs.
Enzyme Inhibition and Molecular Targeting: N-(2-(2-Ethoxyphenoxy)ethyl)-4-Formylbenzamide also holds promise in the inhibition of specific enzymes and proteins involved in disease pathways. The formylbenzamide group can interact with a variety of biological targets, including proteases and kinases, making it an excellent candidate for enzyme inhibition studies. In particular, the compound has shown potential in targeting enzymes that play a central role in cellular signaling, apoptosis, and immune response regulation. This ability to selectively modulate enzyme activity is important for developing drugs that can intervene in complex disease processes, offering a targeted approach with fewer off-target effects.
Anti-inflammatory and Immunomodulatory Applications: Due to its bioactive structure, N-(2-(2-Ethoxyphenoxy)ethyl)-4-Formylbenzamide is being studied for its anti-inflammatory and immunomodulatory properties. Chronic inflammation is a key feature in several diseases, including rheumatoid arthritis, inflammatory bowel disease, and autoimmune conditions. The compound’s ability to interact with inflammatory signaling pathways could make it useful in reducing inflammation and modulating immune responses. By targeting specific inflammatory mediators or pathways, N-(2-(2-Ethoxyphenoxy)ethyl)-4-Formylbenzamide could lead to the development of more effective treatments for these conditions with reduced systemic toxicity.
Catalog | Product Name | CAS | Inquiry |
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BADC-00523 | N-(2-(2-Chloroethoxy)ethyl)-4-Formylbenzamide | 1137575-49-5 | |
BADC-00531 | N-(2-(4-Fluorophenoxy)ethyl)-4-Formylbenzamide | 1225588-22-6 | |
BADC-00532 | N-(2-(3-Fluorophenoxy)ethyl)-4-Formylbenzamide | 1225588-29-3 | |
BADC-00533 | N-(2-(2-Fluorophenoxy)ethyl)-4-Formylbenzamide | 1225705-45-2 | |
BADC-00534 | N-(2-(3-Ethylphenoxy)ethyl)-4-Formylbenzamide | 1225790-49-7 | |
BADC-00535 | N-(2-(4-Ethylphenoxy)ethyl)-4-Formylbenzamide | 1225790-59-9 | |
BADC-00536 | N-(2-(2,6-Dimethylphenoxy)ethyl)-4-Formylbenzamide | 1225936-91-3 | |
BADC-00539 | N-(2-(2-Chlorophenoxy)ethyl)-4-Formylbenzamide | 1225972-65-5 | |
BADC-00540 | N-(2-((2,3-Dihydro-1H-Inden-5-yl)oxy)ethyl)-4-Formylbenzamide | 1225979-81-6 | |
BADC-00541 | N-(2-(Benzo[d][1,3]dioxol-5-yloxy)ethyl)-4-Formylbenzamide | 1226006-03-6 |
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