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Methyl 1-Cbz-azetidine-3-carboxylate is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01931 | -- | $-- | Inquiry |
Methyl 1-Cbz-azetidine-3-carboxylate is a valuable compound in organic synthesis and pharmaceutical research, with several key applications. Here are some of its primary applications:
Peptide Synthesis: Methyl 1-Cbz-azetidine-3-carboxylate is used as a building block in the synthesis of peptides, particularly those containing azetidine ring structures. Its stable carbamate protective group, Cbz, allows for selective deprotection under mild conditions, making it versatile in peptide chemistry. This aids researchers in developing novel peptides for therapeutic and research purposes.
Pharmaceutical Development: This compound serves as an intermediate in the synthesis of various pharmaceuticals, particularly those targeting special ring structures for improved drug efficacy. Its unique reactive properties facilitate the construction of complex molecular architectures in drug discovery. Researchers leverage this versatility to optimize drug candidates, enhancing bioavailability and stability.
Chiral Synthesis: Methyl 1-Cbz-azetidine-3-carboxylate is used in asymmetric synthesis to introduce chirality in pharmaceutical compounds and other active molecules. It acts as a key chiral auxiliary or precursor that enables the synthesis of enantiomerically pure products. This is crucial for the development of drugs where stereochemistry significantly impacts therapeutic outcomes.
Chemical Research: Researchers utilize this compound in studying reaction mechanisms and exploring new synthetic methodologies. Its structure allows chemists to investigate ring-opening reactions and other transformations that can lead to new chemical entities. By understanding its reactivity, scientists can advance the field of synthetic organic chemistry and develop novel synthetic approaches.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
