Name: 1-Amino-8-azido-3,6-dioxaoctane tosylate
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Price

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$--

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Synonyms

H2N-PEG(2)-N3 TosOH; Azido-PEG2-amine tosylate

IUPAC Name

2-[2-(2-aminoethoxy)ethoxy]ethylimino-iminoazanium;4-methylbenzenesulfonic acid

Canonical SMILES

CC1=CC=C(C=C1)S(=O)(=O)O.C(COCCOCCN=[N+]=N)N

InChI

InChI=1S/C7H8O3S.C6H15N4O2/c1-6-2-4-7(5-3-6)11(8,9)10;7-1-3-11-5-6-12-4-2-9-10-8/h2-5H,1H3,(H,8,9,10);8H,1-7H2/q;+1

InChIKey

SKVUFKNZQHNSSN-UHFFFAOYSA-N

Melting Point

53-63°C

Appearance

White to orange to green powder to crystal

Storage

Store at -20 °C

1-Amino-8-azido-3,6-dioxaoctane tosylate, a versatile compound with multifaceted applications in both chemical and biological research, plays a pivotal role in numerous fields. Here are four key applications of this compound presented with high perplexity and burstiness:

Click Chemistry: Immersed in the intricacies of click chemistry, 1-Amino-8-azido-3,6-dioxaoctane tosylate emerges as a dynamic catalyst, seamlessly uniting molecular entities with unparalleled efficiency and specificity. The azido group within the compound readily partakes in azide-alkyne cycloaddition reactions, paving the way for the creation of a diverse array of molecular frameworks and functional biomolecules. These innovations find resonance in domains like drug discovery and materials science, heralding a new era of interdisciplinary exploration.

Bioconjugation: Within the realm of bioconjugation, the prominence of this compound shines brightly, enabling the precise covalent linkage of proteins, nucleic acids, and other biomolecules with finesse. By integrating 1-Amino-8-azido-3,6-dioxaoctane tosylate into biomolecular structures, researchers gain the power to label or modify these entities using a diverse array of probes or therapeutic agents. This transformative approach propels advancements in biological research and the development of tailored therapies, fostering a realm of precision and customization.

Photoaffinity Labeling: Embarking on the intricate journey of photoaffinity labeling, 1-Amino-8-azido-3,6-dioxaoctane tosylate emerges as a central protagonist, unraveling the intricate tapestry of protein interactions and binding sites within biological systems. Upon exposure to UV light, the azido group undergoes a remarkable metamorphosis, forming a reactive nitrene that covalently binds to neighboring protein residues. This groundbreaking technique enables researchers to capture and decode complex protein-protein or protein-ligand interactions within intricate biological environments, shedding light on the unseen connections that govern biological processes.

Polymer Synthesis: Venturing into the realm of polymer chemistry, 1-Amino-8-azido-3,6-dioxaoctane tosylate stands as a catalyst for the creation of bespoke polymers endowed with azido groups, unlocking a realm of endless possibilities. These polymers can be intricately cross-linked or conjugated with additional functional groups using the mechanisms of click chemistry, ushering in a new era of advanced material design. From innovative drug delivery systems to cutting-edge smart coatings, these tailor-made polymers redefine the landscape of material science, offering a canvas for creativity and innovation.