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| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01978 | -- | $-- |
(2S,4R)-Fmoc-4-azido-pyrrolidine-2-carboxylic acid, a synthetic compound commonly employed in peptide and protein chemistry, offers a multitude of applications. Here are four key applications presented with high perplexity and burstiness:
Peptide Synthesis: Serving as a foundational element in solid-phase peptide synthesis, (2S,4R)-Fmoc-4-azido-pyrrolidine-2-carboxylic acid plays a vital role in incorporating azido functionalities into peptides. This strategic maneuver sets the stage for subsequent modifications through click chemistry, underpinning the creation of intricate peptide structures and conjugates with unparalleled complexity and precision.
Protein Labeling: Within the realm of protein chemistry, this compound serves as a catalyst for introducing azido groups that enable precise site-specific labeling of proteins. The reactive azide groups engage in click chemistry reactions with diverse alkyne-containing molecules, facilitating the attachment of probes, tags, or other functional entities. Such targeted labeling methodologies are indispensable for delving into protein dynamics, interactions, and subcellular localization with unprecedented detail and clarity.
Bioconjugation: (2S,4R)-Fmoc-4-azido-pyrrolidine-2-carboxylic acid emerges as a cornerstone in the realm of bioconjugation, where peptides or proteins are seamlessly linked to other biomolecules or surfaces. The versatile azido group serves as a dynamic conduit for molecular attachment via Staudinger ligation or azide-alkyne cycloaddition, shaping the landscape of targeted drug delivery systems, diagnostic tools, and cutting-edge biosensors with intricate and versatile capabilities.
Chemical Biology: In the interdisciplinary domain of chemical biology, this compound stands as an invaluable tool for dissecting protein function and cellular processes. By integrating azido groups into biomolecules, researchers can harness bioorthogonal reactions to intricately probe and manipulate biological systems without disrupting native cellular functions. This strategic approach empowers in-depth investigations into cellular pathways and catalyzes the development of novel therapeutic modalities, pushing the boundaries of scientific exploration and innovation.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
