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Me-PMeOx(50)-N3 (MW 4.3kDa)

  CAS No.:   Cat No.: BADC-01884 4.5  

Me-PMeOx(50)-N3 is a medium molecular weight PEG-like ADC linker with azide functionality, supporting precise bioorthogonal conjugation and improved solubility in antibody-drug conjugates. Keywords: ADC linker, PEG polymer, azide linker, bioorthogonal chemistry, payload conjugation.

Me-PMeOx(50)-N3 (MW 4.3kDa)

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ADC Linker
Molecular Weight
4300(Average)

* For research and manufacturing use only. We do not sell to patients.

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Me-PMeOx(50)-N3, a synthetic polymer with a molecular weight of 43kDa, finds diverse applications in biochemical and materials science. Here are four key applications of Me-PMeOx(50)-N3:

Drug Delivery Systems: Me-PMeOx(50)-N3 plays a crucial role in the development of sophisticated drug delivery systems. Its excellent biocompatibility and ability to form biodegradable carriers make it an excellent choice for encapsulating pharmaceuticals and controlling their release. This approach not only enhances the effectiveness of therapeutic agents but also minimizes their side effects by ensuring precise delivery to the target site of action.

Surface Functionalization: Utilizing this polymer for surface functionalization imparts hydrophilic characteristics and prevents protein adsorption, particularly beneficial for biomedical devices like stents and catheters. These modifications enhance biocompatibility and reduce the risk of thrombosis and infections, consequently extending the longevity and safety of medical implants.

Bioimaging: Me-PMeOx(50)-N3 contributes to bioimaging applications by serving as a component in nanoparticle preparation or contrast agent formulation. Through polymer modification of these particles, researchers can enhance stability and residence time in biological systems, ultimately leading to clearer imaging results essential for precise disease diagnosis and progression monitoring.

Polymer Chemistry Research: Me-PMeOx(50)-N3 holds significance in polymer chemistry research, particularly for exploring poly(2-oxazoline) derivatives' properties. By comprehensively studying its behavior and interactions, researchers can innovate new polymers tailored for specific applications. This knowledge fuels the development of cutting-edge materials in diverse fields ranging from coatings and adhesives to advanced biomaterials.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: KY371 | 1-Cbz-azetidine-3-carboxylic acid | Me-PMeOx(100)-N3 (MW 8.5kDa) | (R)-(+) Azetidine-2-carboxylic acid | SC209 intermediate-2 | DACN(Tos2,6-OH) | Boc-cis-L-4-hydroxyproline methyl ester | H-L-Dbu(N3)-OH HCl | Boc-Ser(O-propargyl)-OH (DCHA) | Boc-L-Phe(4-NH-Poc)-OH | Me-PMeOx(50)-N3 (MW 4.3kDa)
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