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Methyl azetidine-3-carboxylate hydrochloride

  Cat No.: BADC-01915   Purity: >97% 4.5  

Methyl azetidine-3-carboxylate hydrochloride is a protected or functionalized cyclic amino acid building block used in peptide, linker, and small-molecule synthesis. The cyclic scaffold provides a conformationally defined backbone, while the hydroxy, amino, carboxylate, ester, or protecting groups present in the derivative enable stepwise functionalization. The compound can be selected as a synthetic intermediate when a constrained amino acid motif or an additional derivatization site is required. Coupling efficiency, stereochemistry, protecting-group compatibility, and deprotection conditions should be considered in the context of the complete synthetic route.

Methyl azetidine-3-carboxylate hydrochloride

Structure of 100202-39-9

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Molecular Formula
C5H10ClNO2
Molecular Weight
151.59

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Synonyms
Azetidine-3-carboxylic acid methyl ester hydrochloride; 3-Azetidinecarboxylic acid, methyl ester, hydrochloride (1:1)
IUPAC Name
methyl azetidine-3-carboxylate;hydrochloride
SMILES
COC(=O)C1CNC1.Cl
InChI
InChI=1S/C5H9NO2.ClH/c1-8-5(7)4-2-6-3-4;/h4,6H,2-3H2,1H3;1H
InChIKey
UOCWTLBPYROHEF-UHFFFAOYSA-N
Melting Point
93-97°C
Boiling Point
187-192°C at 760 mmHg

Methyl azetidine-3-carboxylate hydrochloride, a versatile compound used in diverse scientific research and industrial applications, boasts a wide range of uses.

Pharmaceutical Research: A cornerstone of pharmaceutical research, methyl azetidine-3-carboxylate hydrochloride plays a pivotal role as a foundational building block for synthesizing cutting-edge drug candidates. Its intricate structure lends itself to a myriad of chemical modifications, facilitating the creation of compounds with enhanced pharmacological properties. Researchers harness the potential of this compound to explore novel therapeutic agents targeting a multitude of diseases.

Chemical Synthesis: Embedded within the realm of organic synthesis, methyl azetidine-3-carboxylate hydrochloride serves as a vital intermediate in constructing complex molecular architectures. The azetidine ring system it harbors can be seamlessly integrated into diverse chemical frameworks, yielding a broad spectrum of functionalized compounds.

Material Science: Delving into material science, this compound finds its niche in the development of polymers and cutting-edge materials. The incorporation of the azetidine moiety imparts distinctive mechanical and thermal properties to polymeric materials, enabling the design of materials tailored for specific applications such as coatings, adhesives, and high-performance composites.

Biochemical Studies: Within the realm of biochemical research, methyl azetidine-3-carboxylate hydrochloride emerges as a powerful tool for investigating enzyme interactions and unraveling biochemical pathways. Its structural characteristics position it as a versatile probe in enzyme-substrate studies, shedding light on enzyme specificity and catalytic mechanisms.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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