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Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01939 | -- | $-- | Inquiry |
Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate, a chemical compound utilized in organic synthesis and pharmaceutical research, exhibits diverse applications.
Chiral Building Block: Serving as a pivotal chiral building block, this compound plays a crucial role in synthesizing intricate molecules, particularly in the pharmaceutical sector. Its specific stereochemistry facilitates the creation of enantiomerically pure substances, essential for designing drugs with targeted activity and minimal side effects. Such chiral building blocks are pivotal in crafting biologically active compounds with precision and efficacy.
Protecting Group Chemistry: The inclusion of the Boc (tert-butoxycarbonyl) group in this compound enables its utilization as a protecting group for amines during multi-step synthetic processes. Protecting groups are indispensable in organic synthesis for safeguarding reactive sites from engaging in undesirable reactions. Notably, the Boc group can be easily eliminated under mild acidic conditions, making it a practical choice for intricate synthetic sequences requiring meticulous protection and deprotection steps.
Research and Development: Widely employed in research environments, Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate facilitates the exploration of novel synthetic pathways and methodologies. Researchers leverage its distinct structure to delve into reaction mechanisms and pioneer innovative synthetic techniques. By broadening the toolkit accessible for chemical synthesis and material advancement, this compound aids in pushing the boundaries of research and development in diverse scientific fields.
Pharmacological Intermediate: Acting as a valuable intermediate in synthesizing pharmacologically active molecules, this compound plays a vital role in the creation of novel therapeutic compounds. Its integration into synthetic pathways empowers researchers to generate innovative molecules with potential therapeutic efficacy. By actively contributing to the realm of drug discovery and development, Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate propels efforts towards enhancing healthcare solutions and advancing pharmaceutical science.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
