Boc-L-Cys(Propargyl)-OH (DCHA)

Boc-L-Cys(Propargyl)-OH (DCHA) Catalog number: BADC-01891

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Boc-L-Cys(Propargyl)-OH (DCHA) is a click chemistry reagent.

Category
ADCs Linker
Product Name
Boc-L-Cys(Propargyl)-OH (DCHA)
Catalog Number
BADC-01891
Molecular Formula
C23H40N2O4S
Molecular Weight
440.64

Ordering Information

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BADC-01891 -- $--
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Description
Boc-L-Cys(Propargyl)-OH (DCHA) is a click chemistry reagent.
Synonyms
(R)-Boc-2-amino-3-propargylsulfanyl-propionic acid dcha
IUPAC Name
N-cyclohexylcyclohexanamine;(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-prop-2-ynylsulfanylpropanoic acid
Canonical SMILES
CC(C)(C)OC(=O)NC(CSCC#C)C(=O)O.C1CCC(CC1)NC2CCCCC2
InChI
InChI=1S/C12H23N.C11H17NO4S/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;1-5-6-17-7-8(9(13)14)12-10(15)16-11(2,3)4/h11-13H,1-10H2;1,8H,6-7H2,2-4H3,(H,12,15)(H,13,14)/t;8-/m.0/s1
InChIKey
CZZODMWFVQDUNT-WDBKTSHHSA-N

Boc-L-Cys(Propargyl)-OH (DCHA),a chemical compound instrumental in biochemistry and pharmaceutical research,finds diverse applications.

Peptide Synthesis:Serving as a foundational component in peptide synthesis,Boc-L-Cys(Propargyl)-OH (DCHA) shines with its propargyl group facilitating precise site modifications that pave the way for introducing bioorthogonal handles,fostering subsequent chemical reactions. This capability is paramount in crafting tailored peptides endowed with distinct properties,tailored for both research and therapeutic endeavors.

Protein Engineering:Within the realm of protein engineering,this compound proves invaluable,seamlessly integrating into proteins to probe structure-function relationships or bestow novel functionalities upon them. The propargyl group offers a versatile site for post-translational modifications,including the heralded click chemistry,enabling the attachment of a myriad of molecular probes or therapeutic agents onto the protein under scrutiny.

Bioorthogonal Chemistry:Found at the nexus of bioorthogonal chemistry,Boc-L-Cys(Propargyl)-OH (DCHA) emerges as a linchpin in enabling chemical reactions within living organisms without impinging on native biochemical processes. The propargyl group within this compound is primed for engaging in reactions such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC),facilitating precise labeling and tracking of biomolecules amidst the intricate milieu of biological systems.

Cancer Research:In the sphere of cancer research,Boc-L-Cys(Propargyl)-OH (DCHA) assumes a pivotal role in the development of cutting-edge therapies. By incorporating this compound into drug delivery systems,researchers can craft targeted treatments tailored to modify cancer cell proteins or signaling pathways with precision. This targeted approach holds the promise of enhancing the efficacy and specificity of cancer therapies,while mitigating side effects,thereby potentially elevating patient outcomes to new heights.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Boc-L-Cys(Propargyl)-OH (DCHA)
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