DBCO-PEG3-TCO is a dual-functional ADC linker combining DBCO and trans-cyclooctene for SPAAC and IEDDA click chemistry, enabling fast, selective bioconjugation in antibody-drug conjugate synthesis.
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Capabilities & Facilities
DBCO-PEG3-TCO, a versatile bioconjugation reagent, offers functionalities tailored for efficient click chemistry applications. Here are four key applications of DBCO-PEG3-TCO:
Bioorthogonal Chemistry: Playing a pivotal role in bioorthogonal reactions, DBCO-PEG3-TCO enables the precise modification of biomolecules at specific sites, all while maintaining the integrity of natural cellular processes. Researchers utilize this reagent to tag proteins, nucleic acids, and other biomolecules in a remarkably specific manner. This technique proves invaluable for dissecting dynamic biological processes within live cells and organisms.
Therapeutic Development: In the realm of drug delivery and therapeutic advancement, DBCO-PEG3-TCO emerges as a key player. It facilitates the conjugation of therapeutic agents with targeted ligands or antibodies, ensuring the precise delivery of drugs to designated cells or tissues. Such targeted delivery not only enhances therapeutic effectiveness but also mitigates off-target effects and toxicity.
Diagnostics: DBCO-PEG3-TCO finds application in diagnostic imaging and assay development, revolutionizing the visualization and detection of specific cellular components or disease markers. By attaching imaging agents or probes to biomolecules of interest, this reagent aids in accurate diagnosis and monitoring of disease progression. Its role in diagnostic precision is paramount for improving patient outcomes and treatment strategies.
Biomolecular Engineering: Powering biomolecular innovation across research and industry, DBCO-PEG3-TCO enables the precise conjugation of functional groups, leading to the creation of novel biomaterials and enzymes with enhanced properties.
Catalog | Product Name | CAS | Inquiry |
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BADC-01010 | DBCO-PEG4-amine | 1840886-10-3 | |
BADC-01017 | DBCO-PEG5-acid | 1870899-46-9 | |
BADC-01536 | DBCO-Peg4-VC-PAB-MMAE | 2129164-91-4 | |
BADC-01073 | DBCO-PEG5-NHS ester | 2144395-59-3 | |
BADC-01077 | DBCO-PEG4-DBCO | 2182601-68-7 | |
BADC-00863 | DBCO-PEG4-Val-Cit-PAB-MMAF | 2244602-23-9 | |
BADC-01089 | DBCO-PEG3 acetic-EVCit-PAB | 2253947-17-8 | |
BADC-00868 | DBCO-(PEG2-VC-PAB-MMAE)2 | 2259318-55-1 | |
BADC-00762 | DBCO-PEG4-VC-PAB-DMEA-PNU159682 | 2259318-56-2 | |
BADC-00751 | DBCO-PEG4-MMAF | 2360411-65-8 |
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