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D-Val-D-Cit-PAB is a synthetic linker compound used in drug development and delivery systems, particularly in ADCs. The linker includes D-valine and D-citrulline, providing specific sites for enzymatic cleavage, and the para-aminobenzyloxycarbonyl group, which facilitates the release of the drug payload once the linker is cleaved within the target cell. This design allows for targeted and controlled drug release, enhancing the efficacy and reducing the toxicity of the therapeutic agents.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01747 | -- | $-- |
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
