Methyltetrazine-amino-PEG4-amine - CAS 2055646-21-2

Methyltetrazine-amino-PEG4-amine - CAS 2055646-21-2 Catalog number: BADC-01962

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Methyltetrazine-amino-PEG4-amine is a heterobifunctional PEG linker.

Category
ADCs Linker
Product Name
Methyltetrazine-amino-PEG4-amine
CAS
2055646-21-2
Catalog Number
BADC-01962
Molecular Formula
C21H32N6O5
Molecular Weight
448.52
Purity
>97%

Ordering Information

Catalog Number Size Price Quantity
BADC-01962 -- $-- Inquiry
Description
Methyltetrazine-amino-PEG4-amine is a heterobifunctional PEG linker.
Synonyms
Tetrazine-PEG4-amine HCl salt; 2055646-21-2; Methyltetrazine-PEG4-amine (hydrochloride); Methyltetrazine-CH2NHCO-PEG4-CH2CH2NH2; Methyltetrazine-PEG4-amine hydrochloride; HY-133505; CS-0119565; 2656478-51-0
IUPAC Name
3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl]propanamide;hydrochloride
Canonical SMILES
CC1=NN=C(N=N1)C2=CC=C(C=C2)CNC(=O)CCOCCOCCOCCOCCN.Cl
InChI
InChI=1S/C21H32N6O5.ClH/c1-17-24-26-21(27-25-17)19-4-2-18(3-5-19)16-23-20(28)6-8-29-10-12-31-14-15-32-13-11-30-9-7-22;/h2-5H,6-16,22H2,1H3,(H,23,28);1H
InChIKey
IWHGCWHSHQWARK-UHFFFAOYSA-N
Storage
Store at -18°C

Methyltetrazine-amino-PEG4-amine, a versatile compound renowned in bioconjugation and drug delivery systems, offers a myriad of applications.

Bioconjugation Techniques: Embracing bioorthogonal chemistry, Methyltetrazine-amino-PEG4-amine plays a pivotal role in bioconjugation strategies. Its methyltetrazine group engages with trans-cyclooctene in a swift and specific manner, streamlining the labeling of biomolecules such as proteins and antibodies. This click reaction stands as a cornerstone for crafting diagnostics and therapeutics focused on precise molecular targeting.

Drug Delivery Systems: Bolstering drug delivery applications, the PEG4 linker within Methyltetrazine-amino-PEG4-amine boosts solubility and circulation time. By coupling therapeutic agents with this compound, researchers enhance drug stability and bioavailability.

Immunoassay Development: In the realm of immunoassay development, Methyltetrazine-amino-PEG4-amine shines as a key component in crafting sensitive and specific assays. Its capacity to adhere to antibodies or antigens allows for the synthesis of conjugates that amplify signal detection in assays, elevating diagnostic test accuracy.

Live Cell Imaging: Within live cell imaging, Methyltetrazine-amino-PEG4-amine emerges as a paramount tool for labeling cellular structures with fluorescent markers. Its exceptional specificity minimizes background noise, empowering researchers to observe cellular processes in real time with unparalleled clarity. This enables the exploration of dynamic biological events and offers insights into cellular behavior across diverse environmental settings.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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