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Methyltetrazine-amino-PEG3-CH2CH2NHBoc is a heterobifunctional PEG linker.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01959 | -- | $-- | Inquiry |
Methyltetrazine-amino-PEG3-CH2CH2NHBoc, a versatile chemical compound utilized in bioconjugation and chemical biology research, plays a pivotal role in various applications.
Bioorthogonal Chemistry: Positioned at the forefront of bioorthogonal chemistry, Methyltetrazine-amino-PEG3-CH2CH2NHBoc serves as a cornerstone for labeling biomolecules within living systems. Its interaction with trans-cyclooctene (TCO) derivatives triggers rapid and specific conjugation reactions in physiological surroundings. This unique feature is paramount in imaging endeavors, enabling scientists to trace biomolecules without disrupting cellular processes.
Drug Delivery Systems: At the intersection of chemistry and medicine, this compound contributes to the development of targeted drug delivery systems by conjugating therapeutic agents to specific targeting molecules. Acting as a pivotal linking group, Methyltetrazine facilitates controlled drug release through click reactions with TCO-functionalized carriers. This precision enhances drug delivery efficiency, ultimately improving therapeutic outcomes.
Protein Modification: Within the realm of protein modification, Methyltetrazine-amino-PEG3-CH2CH2NHBoc plays a crucial role in site-specific labeling of proteins for structural and functional studies. By selectively reacting with appropriately modified proteins, it enables the incorporation of fluorescent probes or other functional groups. This capability is instrumental in unraveling protein interactions, localization, and dynamics within cellular contexts, shedding light on intricate molecular processes.
Antibody Conjugation: Offering a solution in targeted therapy, this compound’s stable linkages with antibodies make it an ideal candidate for antibody-drug conjugates (ADCs). Leveraging bioorthogonal chemistry principles, Methyltetrazine-amino-PEG3-CH2CH2NHBoc facilitates precise attachment of cytotoxic drugs to antibodies. This targeted approach is indispensable for designing cancer therapies that deliver drugs exclusively to cancer cells, minimizing collateral damage and off-target effects.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
