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CAS No.: 2143955-71-7
Cat No.: BADC-01960
Purity: >95%
4.5 
Methyltetrazine-amino-PEG4-CH2CH2NHBoc is a protected ADC linker enabling selective bioorthogonal conjugation with enhanced stability for precision antibody-drug conjugate manufacturing.
Structure of 2143955-71-7
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Methyltetrazine-amino-PEG4-CH2CH2NHBoc is a versatile chemical reagent widely utilized in bioorthogonal chemistry and bioconjugation. Here are four key applications of Methyltetrazine-amino-PEG4-CH2CH2NHBoc:
Bioorthogonal Chemistry: Standing at the forefront of bioorthogonal reactions, Methyltetrazine-amino-PEG4-CH2CH2NHBoc facilitates chemical conjugation within living organisms without disrupting native biochemical processes. Its tetrazine group engages in rapid and selective reactions with trans-cyclooctene, enabling precise molecular tagging in intricate biological systems.
Protein and Antibody Conjugation: Within the realm of protein bioconjugation, Methyltetrazine-amino-PEG4-CH2CH2NHBoc contributes significantly to modifying proteins and antibodies. The amino-PEG4 spacer imparts flexibility, enhancing the solubility and bioavailability of the conjugated molecules. Leveraging its capacity to form stable covalent bonds, this reagent becomes pivotal in crafting targeted therapies and diagnostic tools, demanding exact protein marking for efficacy.
Drug Delivery Systems: Acting as a linchpin in advanced drug delivery systems, Methyltetrazine-amino-PEG4-CH2CH2NHBoc enables the attachment of therapeutic agents to carrier molecules with precision. The PEG moiety enhances the pharmacokinetic profile of the drug, prolonging circulation time and diminishing immunogenicity. This innovative strategy fosters the development of more efficient and targeted drug delivery platforms, elevating treatment effectiveness while curtailing potential side effects significantly.
Biocompatible Material Development: Beyond its primary applications, this reagent also finds utility in synthesizing biocompatible materials vital in diverse medical contexts. The Methyltetrazine group streamlines the functionalization of biomaterials, facilitating the integration of signaling molecules or therapeutic agents. Such materials prove indispensable in fields like tissue engineering, nurturing cell proliferation and tissue regeneration by furnishing essential biological cues and fostering intricate biological interactions for optimal outcomes.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-01962 | Methyltetrazine-amino-PEG4-amine | 2055646-21-2 | |
| BADC-01959 | Methyltetrazine-amino-PEG3-CH2CH2NHBoc | 2141976-32-9 | |
| BADC-01958 | Methyltetrazine-amino-PEG8-CH2CH2NHMal | 2143968-05-0 | |
| BADC-01961 | Methyltetrazine-amino-PEG8-CH2CH2NHBoc | 2143968-21-0 |
Methyltetrazine-amino-PEG4-CH2CH2NHBoc
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Methyltetrazine-amino-PEG4-CH2CH2NHBoc
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