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CAS No.: 2143968-05-0
Cat No.: BADC-01958
Purity: >97%
4.5 
Methyltetrazine-amino-PEG8-CH2CH2NHMal is a heterobifunctional PEG linker cintaining a methyltetrazine group and a maleimide group. The methyltetrazine group is reactive with carboxylic acids and activated esters via click chemistry, and the maleimide group can react with the thiol group in biomolecules.
Structure of 2143968-05-0
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Methyltetrazine-amino-PEG8-CH2CH2NHMal, a specialized chemical compound crucial to bioconjugation and imaging, boasts diverse applications.
Bioorthogonal Chemistry: Embedded in bioorthogonal reactions within living systems, Methyltetrazine-amino-PEG8-CH2CH2NHMal elegantly partakes in chemical interactions without perturbing native biological processes. Its methyltetrazine group showcases swift and discriminative reactivity with trans-cyclooctene (TCO) groups via the inverse electron-demand Diels-Alder (IEDDA) click reaction, enabling precise and efficient labeling of biomolecules amidst intricate biological milieus.
Protein Labeling and Tracking: A pivotal tool for protein labeling and tracking in biological investigations, Methyltetrazine-amino-PEG8-CH2CH2NHMal empowers researchers to tag proteins for fluorescent or radiolabeling utilizing complementary probes. This strategy facilitates real-time monitoring of protein dynamics, localization, and interactions within live cells, shedding illuminating insights on convoluted cellular processes.
Targeted Drug Delivery: In the domain of drug delivery, Methyltetrazine-amino-PEG8-CH2CH2NHMal assumes a crucial role in expediting specific and efficient drug conjugation. By tethering therapeutic agents to carriers armed with TCO, the compound ensures precise drug delivery to specific tissues or cells through the IEDDA click reaction. This targeted delivery approach aids in minimizing side effects and amplifying drug efficacy.
Imaging and Diagnostics: Leveraging Methyltetrazine-amino-PEG8-CH2CH2NHMal for cutting-edge imaging agents in diagnostics, researchers can craft tailor-made imaging probes catering to specific diagnostic exigencies. When coupled with imaging moieties like fluorophores or radiophores, this compound facilitates precise visualization of targets within living organisms. Such strides in diagnostic imaging technologies play a pivotal role in disease detection and monitoring, particularly in conditions such as cancer.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-01962 | Methyltetrazine-amino-PEG4-amine | 2055646-21-2 | |
| BADC-01959 | Methyltetrazine-amino-PEG3-CH2CH2NHBoc | 2141976-32-9 | |
| BADC-01960 | Methyltetrazine-amino-PEG4-CH2CH2NHBoc | 2143955-71-7 | |
| BADC-01961 | Methyltetrazine-amino-PEG8-CH2CH2NHBoc | 2143968-21-0 |
Methyltetrazine-amino-PEG8-CH2CH2NHMal
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Methyltetrazine-amino-PEG8-CH2CH2NHMal
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