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CAS No.: 1831059-64-3
Cat No.: BADC-01849
4.5 
Boc-L-Tyr(PEG(3)-N3)-OH is an azide-functionalized ADC linker intermediate with a PEG3 spacer, enabling efficient copper-free click chemistry for site-specific antibody conjugation, enhancing antibody-drug conjugate stability and targeted drug delivery.
Structure of 1831059-64-3
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Boc-L-Tyr(PEG(3)-N3)-OH is a chemical compound used in the development of advanced biomedical and biochemical applications. Here are some key applications of Boc-L-Tyr(PEG(3)-N3)-OH:
Biomedical Research: Boc-L-Tyr(PEG(3)-N3)-OH is utilized in the development of drug delivery systems, where its PEG moiety imparts increased solubility and biocompatibility. This compound can be conjugated to therapeutic agents, enhancing their targeted delivery to specific tissues or cells. Researchers often employ it in designing new treatments for cancers and chronic diseases.
Protein Engineering: In protein engineering, Boc-L-Tyr(PEG(3)-N3)-OH is used for site-specific modifications of proteins and peptides. The azide group allows for selective conjugation via click chemistry, enabling the attachment of various functional groups or probes. This facilitates the development of protein-based therapeutics and diagnostics with enhanced properties.
Immunoassays: Boc-L-Tyr(PEG(3)-N3)-OH is valuable in the creation of highly specific and sensitive immunoassays. Its PEG linker can help reduce nonspecific binding and increase the stability of assay components. By conjugating this compound to antibodies or antigens, more accurate and reliable diagnostic tests can be developed.
Surface Modification: Boc-L-Tyr(PEG(3)-N3)-OH is used in surface modification of biomaterials to improve biocompatibility and functionality. The PEG segment provides a hydrophilic layer that reduces protein adsorption and cell adhesion, making it ideal for medical implants and devices. This modification enhances the longevity and performance of medical implants.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-01719 | Boc-L-Tyr(2-azidoethyl)-OH | 1434445-10-9 | |
| BADC-01881 | Boc-L-Tyr(PEG(3)-N3)-OH (DCHA) |
Boc-L-Tyr(PEG(3)-N3)-OH
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Boc-L-Tyr(PEG(3)-N3)-OH
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