Name: Me-Tet-PEG3-NH2
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

Methyltetrazine-PEG3-amine; Methyltetrazine-amino-PEG3-amine; Methyltetrazine-CH2NHCO-PEG3-CH2CH2NH2

IUPAC Name

3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-N-[[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl]propanamide

Canonical SMILES

CC1=NN=C(N=N1)C2=CC=C(C=C2)CNC(=O)CCOCCOCCOCCN

InChI

InChI=1S/C19H28N6O4/c1-15-22-24-19(25-23-15)17-4-2-16(3-5-17)14-21-18(26)6-8-27-10-12-29-13-11-28-9-7-20/h2-5H,6-14,20H2,1H3,(H,21,26)

InChIKey

YCRYSSFTLLZVIG-UHFFFAOYSA-N

Me-Tet-PEG3-NH2, a multifunctional linker molecule prevalent in biochemical and biotechnological research, finds diverse applications in scientific endeavors.

Protein Conjugation: Pioneering the realm of molecular connections, Me-Tet-PEG3-NH2 stands as a pivotal player in covalently melding proteins or peptides with a myriad of molecules, be it dyes, drugs, or other proteins. Its polyethylene glycol (PEG) spacer, with its inherent flexibility, mitigates steric hindrance, elevating the solubility and stability of the resultant conjugated entities.

Surface Modification: Embracing the nanotechnological frontier, Me-Tet-PEG3-NH2 emerges as a potent tool in surface modification, accentuating the biocompatibility and functional enhancement of nanoparticles or biosensors. The amino group's versatility facilitates seamless adhesion to diverse surfaces, fostering the assimilation of biologically active molecules.

Polymer Chemistry: In the intricate domain of polymer chemistry, Me-Tet-PEG3-NH2 assumes a foundational role as a cornerstone for synthesizing polymers endowed with tailored properties. Its reactive functional moieties empower the creation of block copolymers or crosslinked networks, customizable to exhibit distinct mechanical or chemical characteristics. These polymers serve a plethora of functions, from acting as carriers for drug delivery to scaffolds in tissue engineering, showcasing the versatility and innovation inherent in polymer science.

Targeted Drug Delivery: Embarking on the forefront of medical advancement, Me-Tet-PEG3-NH2 orchestrates the orchestration of targeted drug delivery systems, acting as a linchpin to affix therapeutic agents to precise targeting ligands. The adaptable nature of the PEG linker streamlines the transportation of drugs to specific cells or tissues, augmenting the therapeutic index while minimizing adverse effects.