Me-Tet-PEG8-NH2 hydrochloride

Me-Tet-PEG8-NH2 hydrochloride Catalog number: BADC-01898

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Me-Tet-PEG8-NH2 (hydrochloride) is an ADC linker containing 2 PEG units.

Category
ADCs Linker
Product Name
Me-Tet-PEG8-NH2 hydrochloride
Catalog Number
BADC-01898
Molecular Formula
C29H49ClN6O9
Molecular Weight
661.19

Ordering Information

Catalog Number Size Price Quantity
BADC-01898 -- $-- Inquiry
Description
Me-Tet-PEG8-NH2 (hydrochloride) is an ADC linker containing 2 PEG units.
IUPAC Name
3-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-N-[[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl]propanamide;hydrochloride
Canonical SMILES
CC1=NN=C(N=N1)C2=CC=C(C=C2)CNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN.Cl
InChI
InChI=1S/C29H48N6O9.ClH/c1-25-32-34-29(35-33-25)27-4-2-26(3-5-27)24-31-28(36)6-8-37-10-12-39-14-16-41-18-20-43-22-23-44-21-19-42-17-15-40-13-11-38-9-7-30;/h2-5H,6-24,30H2,1H3,(H,31,36);1H
InChIKey
UXYNMZYGHRMOMS-UHFFFAOYSA-N

Me-Tet-PEG8-NH2 hydrochloride, a specialized linker compound, plays a vital role in bioconjugation and drug delivery systems.

Bioconjugation: Me-Tet-PEG8-NH2 hydrochloride is a powerhouse in bioconjugation techniques, seamlessly bridging biomolecules like proteins or peptides to therapeutic agents or labels. Its PEG spacer, with its flexibility and steric hindrance reduction, elevates the bioavailability and solubility of the final conjugate. This versatility shines in crafting antibody-drug conjugates or fluorescently labeled probes for precision diagnostic applications.

Drug Delivery Systems: Embark on a journey of targeted drug delivery with Me-Tet-PEG8-NH2 hydrochloride as the cornerstone. By integrating it into liposomes, nanoparticles, or other delivery vehicles, it amplifies targeted delivery to specific cells or tissues.

Surface Modification: Witness the transformative power of Me-Tet-PEG8-NH2 hydrochloride in the realm of surface modification for nanoparticles and medical devices. Its PEG moiety crafts a hydrophilic shield on surfaces, curbing protein adsorption and cellular uptake. This innovative feature is a game-changer in creating biosensors and implantable devices with superior performance and diminished immune response.

Protein Stabilization: Delve into the realm of biochemical research as Me-Tet-PEG8-NH2 hydrochloride steps in to stabilize proteins and enzymes in solution. Through covalently attaching PEG chains to proteins, it bolsters the physical and thermal stability of these biomolecules. This stabilization prowess is indispensable in preserving enzyme activity and extending shelf life, revolutionizing industrial biocatalysis and research landscapes with unwavering reliability.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Me-Tet-PEG8-NH2 hydrochloride
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