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(S)-TCO-PEG3-NH2 is an ADC linker containing 3 PEG units.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01911 | -- | $-- | Inquiry |
(S)-TCO-PEG3-NH2, a versatile compound with widespread applications in chemical biology, is at the forefront of innovation. Here are four key applications presented with high perplexity and burstiness:
Bioconjugation: An indispensable player in bioconjugation strategies, (S)-TCO-PEG3-NH2 acts as a crucial bridge between biomolecules, enabling the attachment of drugs, fluorescent probes, or other functional groups to proteins or nucleic acids. This intricate process is pivotal in the development of targeted therapeutics and cutting-edge diagnostic tools, pushing the boundaries of biochemistry.
Click Chemistry: Embraced in the realm of click chemistry, (S)-TCO-PEG3-NH2 finds its niche in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, offering a bioorthogonal handle that selectively reacts with azides under gentle conditions without disrupting biological processes. This application serves a significant role in live-cell imaging and the precise labeling of biomolecules within living organisms, revolutionizing molecular imaging techniques.
Drug Delivery Systems: Unveiling its potential in enhancing drug solubility and stability, (S)-TCO-PEG3-NH2 emerges as a game-changer in drug delivery systems. By conjugating this compound to drugs, it elevates their pharmacokinetic profiles and bioavailability, while the PEGylation aspect aids in mitigating immunogenic responses and prolonging the therapeutic half-life in the bloodstream. This advancement holds promising implications for the pharmaceutical industry.
Molecular Probes: Stepping into the realm of molecular probes, (S)-TCO-PEG3-NH2 emerges as a key player in specific labeling and detection applications. These conjugates find utility in fluorescence microscopy, flow cytometry, and other analytical techniques, enabling real-time monitoring of biological processes with unparalleled precision. Researchers can now delve into cellular dynamics, protein interactions, and critical events, unraveling the mysteries of life at a molecular level.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
