Inquiry Basket
CAS No.:
Cat No.: BADC-01911
4.5 
(S)-TCO-PEG3-NH2 is a trans-cyclooctene (TCO) based ADC linker featuring a PEG3 spacer and primary amine group, enabling fast bioorthogonal click conjugation in antibody-drug conjugates. It supports efficient payload attachment and enhanced solubility, optimizing targeted drug delivery. Keywords: ADC linker, TCO linker, PEG spacer, bioorthogonal chemistry, payload conjugation.
Structure of
* For research and manufacturing use only. We do not sell to patients.
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | $-- | In stock |
Looking for different specifications? Click to request a custom quote!
Capabilities & Facilities
Popular Publications Citing BOC Sciences Products
(S)-TCO-PEG3-NH2, a versatile compound with widespread applications in chemical biology, is at the forefront of innovation. Here are four key applications presented with high perplexity and burstiness:
Bioconjugation: An indispensable player in bioconjugation strategies, (S)-TCO-PEG3-NH2 acts as a crucial bridge between biomolecules, enabling the attachment of drugs, fluorescent probes, or other functional groups to proteins or nucleic acids. This intricate process is pivotal in the development of targeted therapeutics and cutting-edge diagnostic tools, pushing the boundaries of biochemistry.
Click Chemistry: Embraced in the realm of click chemistry, (S)-TCO-PEG3-NH2 finds its niche in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, offering a bioorthogonal handle that selectively reacts with azides under gentle conditions without disrupting biological processes. This application serves a significant role in live-cell imaging and the precise labeling of biomolecules within living organisms, revolutionizing molecular imaging techniques.
Drug Delivery Systems: Unveiling its potential in enhancing drug solubility and stability, (S)-TCO-PEG3-NH2 emerges as a game-changer in drug delivery systems. By conjugating this compound to drugs, it elevates their pharmacokinetic profiles and bioavailability, while the PEGylation aspect aids in mitigating immunogenic responses and prolonging the therapeutic half-life in the bloodstream. This advancement holds promising implications for the pharmaceutical industry.
Molecular Probes: Stepping into the realm of molecular probes, (S)-TCO-PEG3-NH2 emerges as a key player in specific labeling and detection applications. These conjugates find utility in fluorescence microscopy, flow cytometry, and other analytical techniques, enabling real-time monitoring of biological processes with unparalleled precision. Researchers can now delve into cellular dynamics, protein interactions, and critical events, unraveling the mysteries of life at a molecular level.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-01894 | (S)-TCO-PEG2-Maleimide | ||
| BADC-01903 | (S)-TCO-PEG2-NH2 | ||
| BADC-01910 | (S)-TCO-PEG7-NH2 |
(S)-TCO-PEG3-NH2
Required fields are marked with *
(S)-TCO-PEG3-NH2
Required fields are marked with *
Contact our experts today for pricing and comprehensive details on our ADC offerings.
From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.
Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.
Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.
