Boc-Cystamine-Poc - CAS 2171512-56-2

Boc-Cystamine-Poc - CAS 2171512-56-2 Catalog number: BADC-01835

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Boc-Cystamine-Poc is a click chemistry reagent with cystamine building block.

Category
ADCs Linker
Product Name
Boc-Cystamine-Poc
CAS
2171512-56-2
Catalog Number
BADC-01835
Molecular Formula
C13H22N2O4S2
Molecular Weight
334.45

Ordering Information

Catalog Number Size Price Quantity
BADC-01835 -- $--
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Description
Boc-Cystamine-Poc is a click chemistry reagent with cystamine building block.
IUPAC Name
prop-2-ynyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyldisulfanyl]ethyl]carbamate
Canonical SMILES
CC(C)(C)OC(=O)NCCSSCCNC(=O)OCC#C
InChI
InChI=1S/C13H22N2O4S2/c1-5-8-18-11(16)14-6-9-20-21-10-7-15-12(17)19-13(2,3)4/h1H,6-10H2,2-4H3,(H,14,16)(H,15,17)
InChIKey
RFBADGDLZNRUKZ-UHFFFAOYSA-N

Boc-Cystamine-Poc, a versatile chemical reagent utilized in various biochemical and medical research endeavors, showcases a plethora of essential applications. Here are four key applications presented with heightened levels of perplexity and burstiness:

Protein Modification: A stalwart in the domain of protein thiol group modification, Boc-Cystamine-Poc excels in selectively altering these crucial protein constituents. This reagent adeptly introduces protective groups to shield against undesired reactions in complex synthesis processes. Its utility lies in enabling precise site-specific modifications, a pivotal aspect for deciphering protein functionality and advancing engineering pursuits.

Peptide Synthesis: In the realm of peptide synthesis, Boc-Cystamine-Poc emerges as a pivotal component, serving as a protective shield for cysteine residues. It plays a critical role in preventing disulfide bond formation during peptide construction, ensuring impeccable sequence accuracy and structural integrity. Upon completion of synthesis, these protective groups can be gently removed, preserving the peptide’s integrity without compromise.

Drug Development: Leading the charge in drug discovery and development, Boc-Cystamine-Poc plays a vital role, particularly in designing cysteine-reactive pharmaceutical agents. By integrating this reagent into drug formulation, researchers can create prodrugs that remain dormant until encountering a reducing environment such as the intracellular milieu. This targeted activation approach enhances drug efficacy while minimizing off-target effects, heralding a new era of precision medicine.

Bioconjugation: Venturing into the realm of bioconjugation, Boc-Cystamine-Poc emerges as a champion, orchestrating the fusion of biomolecules, such as linking enzymes to polymers or other proteins. This orchestration leads to complex biomolecular assemblies tailored for a myriad of biotechnological applications. The thiol-reactive nature of Boc-Cystamine-Poc fosters stable and specific conjugations, critical for enhancing the functionality and durability of resulting bioconjugates.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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