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DACN(Tos2,6-OH)

  CAS No.: 2109751-74-6   Cat No.: BADC-01838 4.5  

DACN(Tos2,6-OH) is a maleimide ADC linker featuring tosylate leaving groups at ortho positions, designed for selective cysteine conjugation and improved antibody-drug conjugate stability and drug release control.

DACN(Tos2,6-OH)

Structure of 2109751-74-6

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ADC Linker
Molecular Formula
C21H24N2O5S2
Molecular Weight
448.56

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IUPAC Name
1,5-bis-(4-methylphenyl)sulfonyl-1,5-diazacyclonon-7-yn-3-ol
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)N2CC#CCN(CC(C2)O)S(=O)(=O)C3=CC=C(C=C3)C
InChI
InChI=1S/C21H24N2O5S2/c1-17-5-9-20(10-6-17)29(25,26)22-13-3-4-14-23(16-19(24)15-22)30(27,28)21-11-7-18(2)8-12-21/h5-12,19,24H,13-16H2,1-2H3
InChIKey
PKNMISHKRVDSMU-UHFFFAOYSA-N

DACN(Tos26-OH), a novel chemical compound with diverse applications in biochemistry and molecular research, holds promise across multiple domains. Here are the key applications of DACN(Tos26-OH):

Chemical Synthesis: As a synthetic intermediate, DACN(Tos26-OH) plays a pivotal role in the intricate production of complex organic molecules. Its involvement in multi-step synthesis pathways offers stability and specificity, essential for guiding reactions towards desired outcomes. This makes DACN(Tos26-OH) a valuable reagent in the pharmaceutical and fine chemical industries, pivotal in shaping the development of novel drugs and compounds through meticulous chemical manipulations.

Drug Development: In the realm of drug discovery, DACN(Tos26-OH) emerges as a cornerstone, serving as a fundamental building block for crafting innovative therapeutic agents. Its versatile structure can be tailored to yield derivatives with enhanced pharmacological properties, fueling explorations into structure-activity relationships to optimize the efficacy and safety of potential drug candidates. Researchers utilize this compound as a versatile tool to navigate the complex landscape of drug development, pushing boundaries towards novel medical solutions.

Molecular Probing: Embarking on biochemical explorations, DACN(Tos26-OH) stands as a powerful molecular probe, illuminating the intricate mechanisms underlying enzyme functionality, receptor interactions, and protein-ligand binding dynamics. By leveraging this compound, researchers delve deep into molecular pathways, unraveling the hidden complexities of biological processes and uncovering potential targets for drug intervention, creating a tapestry of new opportunities in drug discovery.

Material Science: Beyond biochemistry, the influence of DACN(Tos26-OH) extends into the realm of material science, fostering the creation of functional polymers and advanced materials. Its unique chemical properties pave the way for the design of materials with tailored characteristics, such as conductivity, biocompatibility, or structural strength, opening new horizons in fields ranging from electronics to medical devices and nanotechnology, driving innovation and technological advancements in diverse applications.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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