DACN(Tos,Ns) is a maleimide-based ADC linker featuring tosylate and nosylate leaving groups, facilitating selective antibody cysteine conjugation with improved payload attachment and ADC stability.
Structure of 1797508-58-7
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Capabilities & Facilities
DACN(TosNs), a versatile chemical reagent utilized in organic synthesis and biochemical research, offers a wide array of applications. Here are four key applications of DACN(TosNs)
Peptide Synthesis: A cornerstone of DACN(TosNs) application lies in peptide synthesis, where its ability to shield amino groups enables precise deprotection and coupling of amino acids, yielding intricate peptide sequences with exceptional efficiency. Researchers heavily rely on this reagent for crafting complex peptides essential for biological investigations and therapeutic advancements.
Protein Modification: Within the realm of biochemical exploration, DACN(TosNs) shines in protein modification by selectively labeling specific amino groups. This targeted alteration facilitates in-depth analysis of protein interactions, localization, and cellular functions. Notably, it aids in generating fluorescently labeled proteins crucial for imaging and tracking studies with remarkable precision.
Organic Chemistry Reactions: DACN(TosNs) stands as a pivotal tool in diverse organic synthesis reactions encompassing nucleophilic substitution and addition reactions. Its proficiency in creating stable intermediates elevates its significance in synthesizing intricate organic compounds spanning from pharmaceuticals to fine chemicals. Chemists leverage its capabilities to streamline synthetic pathways and attain pristine end products of superior purity.
Drug Development: Pharmaceutical innovators wield DACN(TosNs) in the pursuit of novel drug candidates, modifying lead compounds to optimize their pharmacological profiles. By safeguarding specific functional groups, this reagent enables strategic modifications that refine drug efficacy, stability, and safety profiles, critical in the iterative journey of drug discovery and enhancement.
Catalog | Product Name | CAS | Inquiry |
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BADC-01787 | DACN(Tos2) | 1797508-57-6 | |
BADC-01812 | DACN(Tos,Suc-OH) | 2109751-68-8 | |
BADC-01838 | DACN(Tos2,6-OH) | 2109751-74-6 | |
BADC-01768 | DACN(Ms) hydrochloride | 2331322-16-6 | |
BADC-01844 | DACN(Tos) hydrochloride | 2331322-18-8 | |
BADC-01781 | DACN(Ms,Ns) | 2411082-25-0 | |
BADC-01818 | DACN(Tos,Suc-NHS) | 2411082-26-1 | |
BADC-01852 | DACN(Tos,Mal) | 2411082-28-3 |
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