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DACN(Ms) hydrochloride

  CAS No.: 2331322-16-6   Cat No.: BADC-01768 4.5  

DACN(Ms) hydrochloride is a disulfide ADC linker intermediate with mesylate leaving group, designed for controlled intracellular payload release and stable conjugation in antibody-drug conjugates. Keywords: ADC linker, disulfide linker, mesylate leaving group, cleavable linker, drug delivery.

DACN(Ms) hydrochloride

Structure of 2331322-16-6

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ADC Linker
Molecular Formula
C8H15ClN2O2S
Molecular Weight
238.74

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IUPAC Name
1-methylsulfonyl-1,5-diazacyclonon-7-yne;hydrochloride
Canonical SMILES
CS(=O)(=O)N1CCCNCC#CC1.Cl
InChI
InChI=1S/C8H14N2O2S.ClH/c1-13(11,12)10-7-3-2-5-9-6-4-8-10;/h9H,4-8H2,1H3;1H
InChIKey
AGDNMJAXTZEOKM-UHFFFAOYSA-N

DACN(Ms) hydrochloride, a chemical compound with diverse applications in bioscience and industry, offers a multitude of uses in various fields. Here are four key applications of DACN(Ms) hydrochloride:

Pharmaceutical Synthesis: Serving as a pivotal intermediate in pharmaceutical synthesis, DACN(Ms) hydrochloride plays a crucial role in creating a spectrum of pharmaceutical compounds. Its intricate structure allows for the incorporation of specific functional groups, facilitating the synthesis of complex drug molecules. This characteristic positions it as an indispensable component in the quest for novel therapeutic agents.

Agrochemical Production: Within the agrochemical industry, DACN(Ms) hydrochloride emerges as a cornerstone for the creation of pesticides and herbicides. Leveraging its chemical properties, industry professionals can modify active ingredients to boost efficacy and stability. This enhancement translates into the production of environmentally friendly and highly effective agricultural chemicals, propelling progress in sustainable farming practices.

Chemical Research: In the realm of chemical research, DACN(Ms) hydrochloride emerges as a versatile reagent, offering a vital tool for organic chemistry endeavors. Often utilized in reactions necessitating selective protection or deprotection of functional groups, this compound serves as a critical resource for researchers engaged in the synthesis of intricate organic compounds and natural products. Its versatility and utility contribute significantly to the advancement of chemical science.

Biotechnology: Within the dynamic field of biotechnology, DACN(Ms) hydrochloride finds application in the modification of biomolecules such as proteins and nucleic acids. Through the integration of this compound, researchers can manipulate the properties of biomolecules to explore their functionality or enhance their performance across diverse applications. This utilization holds profound implications for drug development, diagnostics, and the creation of therapeutic bioconjugates.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: DACN(Tos,Suc-NHS) | Cyclooctyne-O-amido-PEG2-NHS ester | Cyclooctyne-O-amido-PEG3-NHS ester | BCN-endo-PEG2-maleimide | NH-bis-PEG2 | Fmoc-Lys(IvDde)-OH | N3-L-Cit-OH | DACN(Tos2) | DACN(Ms) hydrochloride
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