DACN(Tos,Mal) - CAS 2411082-28-3

DACN(Tos,Mal) - CAS 2411082-28-3 Catalog number: BADC-01852

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DACN(Tos,Mal) is a click chemistry reagent.

Category
ADCs Linker
Product Name
DACN(Tos,Mal)
CAS
2411082-28-3
Catalog Number
BADC-01852
Molecular Formula
C22H25N3O5S
Molecular Weight
443.52

Ordering Information

Catalog Number Size Price Quantity
BADC-01852 -- $--
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Description
DACN(Tos,Mal) is a click chemistry reagent.
IUPAC Name
1-[4-[5-(4-methylphenyl)sulfonyl-1,5-diazacyclonon-7-yn-1-yl]-4-oxobutyl]pyrrole-2,5-dione
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)N2CCCN(CC#CC2)C(=O)CCCN3C(=O)C=CC3=O
InChI
InChI=1S/C22H25N3O5S/c1-18-7-9-19(10-8-18)31(29,30)24-15-3-2-13-23(14-5-16-24)20(26)6-4-17-25-21(27)11-12-22(25)28/h7-12H,4-6,13-17H2,1H3
InChIKey
KDWOODHHRYVLSK-UHFFFAOYSA-N

DACN (Tos Mal), a dual-acting compound comprising tosyl and malonyl groups, holds multifaceted applications in various bioscience domains. Here are four pivotal applications of DACN (Tos Mal):

Bioconjugation: Utilizing DACN (Tos Mal) as a pivotal linker in bioconjugation methodologies enables the attachment of biomolecules, such as proteins and antibodies, to diverse surfaces or molecules. This process engenders multifunctional complexes essential in diagnostics, therapeutics, and biosensors. The dual functionality of DACN (Tos Mal) facilitates selective and robust conjugation, elevating the effectiveness of the resultant bioconjugates.

Chemical Synthesis: Bridging the gaps in synthetic organic chemistry, DACN (Tos Mal) serves as a dynamic intermediate crucial for forging various carbon-carbon and carbon-heteroatom bonds via nucleophilic substitution and condensation reactions. This versatility streamlines the synthesis of an array of chemical entities, spanning from pharmaceuticals to agrochemicals.

Polymer Chemistry: Navigating the intricacies of polymer science, DACN (Tos Mal) emerges as a potent tool in the design and synthesis of functional polymers. Its reactive groups can orchestrate polymerization initiation or be seamlessly integrated into polymer frameworks to imbue bespoke functional properties. This application is instrumental in sculpting advanced materials with customized functionalities, drafted for applications in coatings, adhesives, and biomedical devices.

Drug Delivery Systems: Spearheading the frontier of targeted drug delivery systems, DACN (Tos Mal) plays a pivotal role in enhancing therapeutic precision. By conjugating DACN to drug compounds or carrier vehicles like nanoparticles, researchers can orchestrate site-specific drug release, thereby amplifying therapeutic efficacy. This innovative approach tackles challenges pertaining to drug solubility, stability, and regulated release, redefining the landscape of drug delivery mechanisms.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Val-Lys(Boc)-PAB | DACN(Tos,Mal)
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