Inquiry Basket
MC-VC-PABC-DNA31 is a drug-linker conjugate for ADC with potent antitumor activity by using DNA31 (a potent RNA polymerase inhibitor), linked via the ADC linker MC-VC-PABC.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-00853 | -- | $-- | Inquiry |
MC-VC-PABC-DNA31, a potent linker-drug conjugate, is a cornerstone in targeted cancer therapies, blending a powerful drug with a specific delivery mechanism. Here are four key applications of MC-VC-PABC-DNA31:
Targeted Drug Delivery: Serving as an innovative carrier, MC-VC-PABC-DNA31 transports cytotoxic drugs directly to cancer cells, all while minimizing harm to healthy tissues. By tethering a therapeutic agent to a targeting moiety, the conjugate selectively binds to overexpressed receptors on tumor cells. This targeted strategy amplifies drug effectiveness while mitigating systemic toxicity.
Antibody-Drug Conjugates (ADCs) Development: MC-VC-PABC-DNA31 assumes a pivotal role in crafting ADCs tailored to combat diverse cancer types. The conjugate harnesses a stable linker to unleash the drug within the cancer cell milieu.
Pharmacokinetic Studies: The MC-VC-PABC-DNA31 linker becomes a linchpin in unraveling the pharmacokinetics of drug conjugates, furnishing invaluable insights into their absorption, distribution, metabolism, and excretion. Through scrutinizing these facets, researchers can fine-tune the application of linker-drug conjugates for optimal therapeutic results.
Customer Support
Providing excellent 24/7 customer service and support
Project Management
Offering 100% high-quality services at all stages
Quality Assurance
Ensuring the quality and reliability of products or services
Global Delivery
Ensuring timely delivery of products worldwide
BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
