webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More

Alkyne-PEG2-iodide

  CAS No.: 1234387-33-7   Cat No.: BADC-01696   Purity: NMR 1H, GC-MS (95%) 4.5  

Alkyne-PEG2-iodide is a bifunctional ADC linker combining alkyne and iodide reactive groups with a PEG2 spacer. It facilitates click chemistry and nucleophilic substitution for selective and stable payload conjugation in antibody-drug conjugates.

Alkyne-PEG2-iodide

Structure of 1234387-33-7

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C7H11IO2
Molecular Weight
254.07
Shipping
Storage: 24 months after receival at -20 °C in the Dark. Transportation: at room temperature for up to 3 weeks.

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
3-[2-(2-Iodoethoxy)-ethoxy]-propyne; 1-iodo-2-[2-(prop-2-yn-1-yloxy)ethoxy]ethane
IUPAC Name
3-[2-(2-iodoethoxy)ethoxy]prop-1-yne
Canonical SMILES
C#CCOCCOCCI
InChI
InChI=1S/C7H11IO2/c1-2-4-9-6-7-10-5-3-8/h1H,3-7H2
InChIKey
KRKPKEAEPAZGGU-UHFFFAOYSA-N
Solubility
Soluble in water, polar organic solvents
Appearance
Colorless to yellow oil
Storage
Storage: 24 months after receival at -20 °C in the Dark. Transportation: at room temperature for up to 3 weeks.

Alkyne-PEG2-iodide, a versatile chemical compound, finds myriad applications in bioconjugation and biochemical domains. Here are four key applications of Alkyne-PEG2-iodide, presented with high perplexity and burstiness:

Click Chemistry: Embracing the realm of click chemistry, Alkyne-PEG2-iodide emerges as a cornerstone, facilitating bioorthogonal reactions with finesse. By pairing with azide-functionalized molecules, it orchestrates the precise and exclusive labeling of biomolecules. This intricate dance enables the exploration of protein-protein interactions, delving into the inner workings of cellular processes, and forging paths in diagnostic tool development.

Drug Delivery: Harnessing the PEGylation prowess of Alkyne-PEG2-iodide, researchers delve into the realm of drug delivery systems, where this compound plays a pivotal role. Through strategic attachment to therapeutic agents, it elevates solubility, stability, and bioavailability of drugs, culminating in heightened therapeutic efficacy and mitigated side effects.

Immunoassays: Stepping into the arena of immunoassays, Alkyne-PEG2-iodide takes center stage, driving advancements in diagnostics and clinical research. Its application in modifying antibodies or antigens ushers in a new era of conjugation with reporter molecules like fluorophores or enzymes, enabling the detection of target analytes with precision. Immunoassays emerge as a linchpin in biomarker discovery, paving the way for groundbreaking insights in clinical settings.

Surface Functionalization: A pioneer in surface functionalization, Alkyne-PEG2-iodide empowers the field of biomaterials and nanoparticles. By introducing reactive alkyne groups, it sets the stage for subsequent conjugation with diverse ligands, such as peptides or oligonucleotides, heralding innovations in biosensor development, tissue engineering, and targeted drug delivery systems.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker/Peptide Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker/Hydrazone Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Anetumab ravtansine | m-PEG6-SS-PEG6-methyl | SG3199 | Azido-PEG8-propionic acid | Azido-PEG5-propionic acid | Azido-PEG4-propionic acid | Fmoc-Ala-Ala-Asn(Trt)-OH | m-PEG8-COOH | Bis-PEG1-NHS ester | m-PEG2-NHS ester | Alkyne-PEG2-iodide
Send Inquiry
Verification code
Inquiry Basket