alpha-Man-teg-N3 is an azide-functionalized mannose-based ADC linker designed for targeted delivery applications and bioorthogonal conjugation in antibody-drug conjugates. Keywords: ADC linker, azide linker, mannose linker, targeted drug delivery.
Structure of 246855-76-5
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Capabilities & Facilities
Alpha-Man-teg-N3, a synthetic sugar derivative with manifold applications in biochemistry and medicine, serves as a pivotal component in diverse fields. Here are four key applications of alpha-Man-teg-N3, intricately presented with high perplexity and burstiness.
Glycobiology Research: Imbued with significance, alpha-Man-teg-N3 is a linchpin in the exploration of carbohydrate structures and functionalities. Researchers harness this compound to meticulously trace and scrutinize glycan interactions and pathways within cellular domains. This comprehension stands as a cornerstone for unraveling the intricate roles of glycosylation in maintaining health equilibrium and combating diseases.
Diagnostic Imaging: Unveiling a realm of possibilities, this compound finds utility in developing imaging agents for diagnostic ventures. By conjugating alpha-Man-teg-N3 with fluorescent or radioactive tracers, it furnishes a visual pathway to discern glycan distributions at micro and macroscopic scales within tissues and cells. This technological advancement plays a pivotal role in diagnosing and monitoring diseases where altered glycosylation patterns stand as harbingers, including the realms of cancer and autoimmune maladies.
Vaccine Development: Propelling innovation in medical science, alpha-Man-teg-N3 plays a decisive role in the evolution of glycan-centric vaccines. Infusing this compound into vaccine matrices enhances the immunogenicity surrounding target antigens, promising a more robust defense against pathogens sporting glycan-rich surfaces, be it bacteria or viruses. This inventive strategy heralds a new era in vaccine efficacy and resilience against ever-evolving microbial adversaries.
Therapeutic Targeting: Paving the path to precision medicine, alpha-Man-teg-N3 assumes a pivotal role in crafting targeted therapeutic modalities. By intricately linking therapeutic agents to this compound, drug developers engineer a pathway for treatments to specifically target glycan-bearing cells or tissues. This precision-guided approach not only bolsters drug potency but also mitigates adverse effects by ensuring therapeutic payloads reach their designated destinations with pinpoint accuracy.
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