Name: Alkyne-PEG4-SS-PEG4-alkyne
Brand: BOC Sciences
Rating: 5 (1 reviews)

Size

Price

Stock

Quantity

$--

In stock

IUPAC Name

Canonical SMILES

C#CCOCCOCCOCCOCCSSCCOCCOCCOCCOCC#C

InChI

InChI=1S/C22H38O8S2/c1-3-5-23-7-9-25-11-13-27-15-17-29-19-21-31-32-22-20-30-18-16-28-14-12-26-10-8-24-6-4-2/h1-2H,5-22H2

InChIKey

NSDZQVXLZWRJNH-UHFFFAOYSA-N

Solubility

10 mm in DMSO

Appearance

Colorless oil

Shelf Life

0-4°C for short term (days to weeks), or -20°C for long term (months).

Shipping

Room temperature, or blue ice upon request.

Storage

-20°C

Alkyne-PEG4-SS-PEG4-alkyne is a bifunctional compound featuring polyethylene glycol (PEG) chains and alkyne groups, which facilitates bioconjugation and molecular engineering. Here are some key applications of Alkyne-PEG4-SS-PEG4-alkyne:

Drug Delivery Systems: Alkyne-PEG4-SS-PEG4-alkyne is used in the development of drug delivery systems, particularly for creating stable linkages between drug molecules and carrier vehicles such as liposomes or nanoparticles. The alkyne groups enable click chemistry reactions, allowing for precise conjugation. This results in enhanced drug delivery efficiency and targeted therapy solutions.

Protein Engineering: In protein engineering, Alkyne-PEG4-SS-PEG4-alkyne is employed to functionalize proteins through covalent attachment. The PEG chains provide a hydrophilic spacer, improving protein solubility and stability, while the terminal alkynes facilitate bioorthogonal reactions. This enables the creation of modified proteins with desired properties for research and therapeutic applications.

Bioconjugation: Alkyne-PEG4-SS-PEG4-alkyne serves as a versatile linker in bioconjugation techniques to join biomolecules such as antibodies, peptides, and nucleic acids. The compound's dual alkyne functionalities allow for efficient "click" reactions with azide-labeled counterparts, forming stable conjugates. This is crucial in diagnostic assays, imaging, and biosensor development.

Surface Modification: Alkyne-PEG4-SS-PEG4-alkyne is used in surface modification to create functionalized surfaces for biosensor chips and medical implants. The PEG segments help in reducing non-specific binding and improving biocompatibility, while the alkyne groups allow for the attachment of various biomolecules. This facilitates the development of advanced diagnostic tools and biomedical devices with enhanced performance.